Protein Info for PS417_11165 in Pseudomonas simiae WCS417
Annotation: omega amino acid--pyruvate aminotransferase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 46% identical to OAPT_PSEPU: Omega-amino acid--pyruvate aminotransferase from Pseudomonas putida
KEGG orthology group: K00822, beta-alanine--pyruvate transaminase [EC: 2.6.1.18] (inferred from 72% identity to aaa:Acav_3442)Predicted SEED Role
"Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18)" in subsystem Pyruvate Alanine Serine Interconversions (EC 2.6.1.18)
MetaCyc Pathways
- superpathway of coenzyme A biosynthesis II (plants) (9/10 steps found)
- β-alanine biosynthesis II (5/6 steps found)
- β-alanine degradation II (2/2 steps found)
KEGG Metabolic Maps
- Alanine and aspartate metabolism
- Propanoate metabolism
- Valine, leucine and isoleucine degradation
- beta-Alanine metabolism
Isozymes
Compare fitness of predicted isozymes for: 2.6.1.18
Use Curated BLAST to search for 2.6.1.18
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A1N7UGK4 at UniProt or InterPro
Protein Sequence (431 amino acids)
>PS417_11165 omega amino acid--pyruvate aminotransferase (Pseudomonas simiae WCS417) MTSSLWAPFTAMRPFNRQPMLFDRAAGMHYTTTEGRDVLDAMAGLWCVNAGHGQPRIVEA IREAAGRLDFVSSFKMSHPAALTLADQLVAKAPANLDKVFFTNSGSEAVDTALKIARAYH QARGDSRRTKLIGRAKGYHGMGFGGLSVSGIGRQKRDFGPLLGDVAHLPLPYDAGSRFSL GQPEQGAHYADALLHLLEVHDPATVAAVIVEPVTGSGGVYAPPLGYLQKLREICDRHGLL LIFDEVITGFGRVGHGFAAEAFGVTPDLMTLAKGLTNGAVPMGGVLVSGAVYEAFMQGPE QAIELMHGYTYSAHPLACAAGLATLEVHEELGLNAHVRQIAPLWQNTALALREQALVLDV RAIGLLCAVELKPREGAPGARAAGVAQRCFEAGVLVRASGENIVLSPPLIINQEQVAQVF STLGKALEATR