Protein Info for GFF2167 in Xanthobacter sp. DMC5

Annotation: Catecholate siderophore receptor Fiu

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 781 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details PF07715: Plug" amino acids 75 to 175 (101 residues), 82 bits, see alignment E=4.4e-27 PF00593: TonB_dep_Rec_b-barrel" amino acids 249 to 751 (503 residues), 159.7 bits, see alignment E=2.3e-50

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 72% identity to sno:Snov_2373)

Predicted SEED Role

"TonB-dependent siderophore receptor" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (781 amino acids)

>GFF2167 Catecholate siderophore receptor Fiu (Xanthobacter sp. DMC5)
MGALSTLRPAMSRSTVSAGLAMTLSAVPLAEAFAQQATAPSGTDADLPTIVVDADGEPVN
SLEATTGLSRLPGTLQDTPQTVTVISQQTMQQQGVTTLEQALRNVPGVTVGIGEGGGGMN
GDQFRIRGFQAKGDVFVNGLRDFGVYVRDSFAYENVEVFKGPSSESFGSGTTGGAINMQL
KQAHRGDKYDVDGQFGSGPLYRGVFDFNKQIDDTTAARIVGMFNDQNIVDRDHVEANRYG
LMGSLGFGLGTNQTLYLNYLYQHGDRTPDYGVPVVTPLFNDVKKFGAVGQPVTEWGVPRS
NFYGKETDRDITNTNMFTANYKNEINDWLTFTNDSRVGYYTRDFATSVPGCGNGSTSTVP
ATPTTYATSCTAAFFAGNNPAITFGGGNPGYLQESLAAENVATMIAKFNTGFLRHELVAG
IDYYFVNDNRTLVSVNGSKGLSTIWNPVYANTTGYFLYENPFGNNGQKVSNTYDFGAFAS
DRIWFTDQLSILGGIRWDNYSTDYDYWCVVTTGTCPGSKEKKAWVYTNSDTRFWSPKASL
IWEPTKTQTYYVSYAKSFSPQGGFPTNDVTVVNPVQNNLSPEDNETWETGAKVSVLDGRL
GLTAALFRIDKSNVFYTDPVTGDSVESGENQRVQGVELGVTGTITDAWTIQAGYAYYASE
ILTSTTLSYVGNQVPFVSPNNFTLWTTYDLIKGGVVRMIPGQLLVGGGITYADGYFTNSA
NTAIIPETFSLDALISYKHENYRVALNGYNLTNALNYSAGWGNRAIPASGRSFTLSVGYT
F