Protein Info for GFF2156 in Variovorax sp. SCN45

Annotation: Deoxyribodipyrimidine photolyase (EC 4.1.99.3)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 499 PF00875: DNA_photolyase" amino acids 16 to 171 (156 residues), 160.6 bits, see alignment E=3.5e-51 PF03441: FAD_binding_7" amino acids 284 to 489 (206 residues), 293.6 bits, see alignment E=6.2e-92

Best Hits

KEGG orthology group: K01669, deoxyribodipyrimidine photo-lyase [EC: 4.1.99.3] (inferred from 93% identity to vpe:Varpa_5222)

Predicted SEED Role

"Deoxyribodipyrimidine photolyase (EC 4.1.99.3)" (EC 4.1.99.3)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.99.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (499 amino acids)

>GFF2156 Deoxyribodipyrimidine photolyase (EC 4.1.99.3) (Variovorax sp. SCN45)
MPPILLAVDKTYPKGLMWFRRDLRVDDNAALYRALRACRQVVCVFVFDKAILDPLPTVDR
RVEFIRESLLELEAELRALGGALIVRHGLAAQEIPALAHDLDVQAVFANRDDEPDALERD
AKVFGALANAGVTFHTYKDSTVFDRDEVMTKTGQPYTVFTPYKRAWLAKVDSFFLKSYPV
RSHADALVPPPEAYREPMPSLGELGFEKSNLSTLEIPTGTRGAGTLFEDFFERIDRYDEA
RNFPAVRGPSYMGVHLRFGTVSIRQMASLAHQLSLQGNAGAATWLSELIWRDFYFQILAH
FPYVHTGGESKSFRPEYDKIQWHHGKHADQLFEAWCQGRTGYPLVDAAMLQINQSGYMHN
RLRMVVASFLCKDLGLDWRRGEAYFALHLNDFELASNNGGWQWASSSGCDAQPYFRIFNP
VTQSERFDPEGKFIRRYLPQLAGLSNAAIHAPWQASPVELEAAGIKLGETYPKPVVDHAE
AREKTLQRYGVARAKALQK