Protein Info for GFF2147 in Xanthobacter sp. DMC5

Annotation: Bicarbonate transport ATP-binding protein CmpD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 279 PF00005: ABC_tran" amino acids 46 to 185 (140 residues), 110.9 bits, see alignment E=7.5e-36

Best Hits

Swiss-Prot: 51% identical to Y4187_BRUSU: Putative ATP-binding protein BRA1187/BS1330_II1178 (BRA1187) from Brucella suis biovar 1 (strain 1330)

KEGG orthology group: K02049, sulfonate/nitrate/taurine transport system ATP-binding protein (inferred from 85% identity to rpx:Rpdx1_4375)

Predicted SEED Role

"ABC transporter, ATP-binding component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (279 amino acids)

>GFF2147 Bicarbonate transport ATP-binding protein CmpD (Xanthobacter sp. DMC5)
MLANASLMSPAAPGLAPQFSPEDVQIDIRNVGKVYGSKVEAPVIALDGVTLRIRRGEFIS
LLGPSGCGKSTLLGIIAGFQSATSGQLLQDGRPITKPDPSRTVVFQDYALFGWMTVQQNV
EFGLKAKGMPKAERAEIARALIATVRLNGFEDKFPHQMSGGMKQRAAIARALAPDPDILL
MDEPFGALDAQTRVLLQEEIARISSEAGKTVIFVTHGIDEAVFLADRVVVMSPRPGRVRE
EVLVPLPRPRTAEMRSDPWFVSTVNDLWETLKPEWQKGE