Protein Info for GFF2131 in Variovorax sp. SCN45

Annotation: Putative protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 616 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF17899: Peptidase_M61_N" amino acids 23 to 195 (173 residues), 152 bits, see alignment E=1.7e-48 PF05299: Peptidase_M61" amino acids 302 to 418 (117 residues), 165.4 bits, see alignment E=6.2e-53

Best Hits

KEGG orthology group: None (inferred from 90% identity to vpe:Varpa_5250)

Predicted SEED Role

"protease, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (616 amino acids)

>GFF2131 Putative protease (Variovorax sp. SCN45)
MAAKAPVRRSAAAVAAPVAGVRFRVECADLHARLFGVTLTIDAPAARQRVSLPVWIPGSY
LVREFAKNLQGLRATQGRRKPTLTQLDKCSWLVECTPGQPLVLNYQVCAYDNSVRTAWLD
AERGFFNGTSVCLRVEGQTDAPHALEIVAPVLADDAPRWSCATALVPLKADRHGFGSYQA
AGYDELADSPVEMGAFWSAEFEACGVPHRFVVAGAAASFDGDRLIADTKAICEAEMRFWH
GDKAGKRGGPKLPIDRYVFMLNAVDDGYGGLEHRHSTALICNRRDLPQRGEKKKQPEGYT
TLMGLISHEYFHTWNVKRMRPGEFARYDYSQENYTQLLWFFEGFTSYYDDLLLRRAGRID
DAAYLRLLNKTINQVMQTPGRLVQPVADASFDAWVKYYRQDEQTPNSTVSYYTKGALVAL
CFDLTLRHEGKGTLDDVMRHLWTHGGGGPISEADIAAALEAVSGRSYAVELARWVHSTEE
LPLAQLLRAHGVATLEDPSQQAQALGLRVAEANGSVQVKVVLRGGPAEKAGFSANDEWIG
IELPAVGKRGQQRPAQAWRIAKLDDLALYLGDATKCTAIVARDRKLIRLPLALPTNATTW
RLFAHDATKVAGWLAG