Protein Info for GFF2115 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Predicted aminoglycoside phosphotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 transmembrane" amino acids 285 to 303 (19 residues), see Phobius details PF01636: APH" amino acids 23 to 240 (218 residues), 178 bits, see alignment E=1.4e-56

Best Hits

KEGG orthology group: None (inferred from 54% identity to xau:Xaut_4078)

Predicted SEED Role

"Predicted aminoglycoside phosphotransferase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (340 amino acids)

>GFF2115 Predicted aminoglycoside phosphotransferase (Hydrogenophaga sp. GW460-11-11-14-LB1)
MQTETLDAFLRQSIEGLSGPMRLQKIGGGQSNPTFFVSYDQRELVLRKKPDGEVLPSAHA
VDREYRVMKALAATALPVPPVLLYHAEPDVVGTPFYVMERVPGRVFNDNAAPGIAPDERR
AIYLAMADTLATLHSVDWQAAGLTGYGKPGGYFQRQLGRWQQQWMLSRIDPIPAIDQLLD
WLGRHLPADDGETTIAHGDFKLNNLLFHPTEPRVVAVLDWELATLGHPLADVAFNTVAWR
TLPGEYGGIRGLDLAALGIPSEHEYLAHYYRRTGRDDPARQATPFHWAFALMRWAVIFAG
IAARAARGSATSDNAAEVGVLAVALAQRGLEAIDTPMPPL