Protein Info for GFF2094 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: TRAP-type C4-dicarboxylate transport system, large permease component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 transmembrane" amino acids 6 to 34 (29 residues), see Phobius details amino acids 54 to 74 (21 residues), see Phobius details amino acids 92 to 124 (33 residues), see Phobius details amino acids 138 to 164 (27 residues), see Phobius details amino acids 170 to 192 (23 residues), see Phobius details amino acids 212 to 234 (23 residues), see Phobius details amino acids 240 to 256 (17 residues), see Phobius details amino acids 272 to 294 (23 residues), see Phobius details amino acids 314 to 343 (30 residues), see Phobius details amino acids 355 to 377 (23 residues), see Phobius details amino acids 396 to 421 (26 residues), see Phobius details PF06808: DctM" amino acids 12 to 415 (404 residues), 407.6 bits, see alignment E=3e-126 TIGR00786: TRAP transporter, DctM subunit" amino acids 17 to 419 (403 residues), 461.2 bits, see alignment E=1.3e-142

Best Hits

Swiss-Prot: 51% identical to YIAN_ECOLI: 2,3-diketo-L-gulonate TRAP transporter large permease protein YiaN (yiaN) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 69% identity to rhi:NGR_b08890)

MetaCyc: 51% identical to 2,3-diketo-L-gulonate:Na+ symporter - membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-235

Predicted SEED Role

"TRAP-type C4-dicarboxylate transport system, large permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (425 amino acids)

>GFF2094 TRAP-type C4-dicarboxylate transport system, large permease component (Hydrogenophaga sp. GW460-11-11-14-LB1)
MTFTIFLGALGGAMAIGMPIAFALLVTGAALMIFSGEFDATLLSQKIVEGADSFPLLAIP
FFMLAGELMNAGGISRRIVDFALAWIGHIRGGLGIVAIAAAVIMAAISGSAAADAAALTA
MLIPMMRKAGYDVARSGGLIAAGSVIAPVLPPSIALIVFGVIANVSIGKLFMAAIVPGLL
MGVALVATWLWISRKEPGRMQPRTPMPERLRITARATWALIMPIGIVGGMKLGVFTPTEA
AVVAAVYAFIVGMFVYRELTWRMLYPLLLSSAKASAAVVFLIATALVSAWLITVSEIPQQ
VSDMLQPLIANPTLLMFAMMALVIVVGTALDFSPTLLILTPILMPIVREAGIDPVYFGVL
FVMNNAIGLITPPVGIVLNVVCSGARLQMGQLMKGLWPFLIAEVAVLFLLVIFPSIVLVP
LRWLF