Protein Info for GFF2093 in Variovorax sp. SCN45

Annotation: Fatty acid hydroxylase family (carotene hydroxylase/sterol desaturase)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 580 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 54 to 78 (25 residues), see Phobius details amino acids 90 to 107 (18 residues), see Phobius details amino acids 145 to 172 (28 residues), see Phobius details amino acids 311 to 332 (22 residues), see Phobius details amino acids 341 to 361 (21 residues), see Phobius details amino acids 379 to 405 (27 residues), see Phobius details amino acids 414 to 435 (22 residues), see Phobius details amino acids 441 to 464 (24 residues), see Phobius details amino acids 471 to 489 (19 residues), see Phobius details amino acids 497 to 518 (22 residues), see Phobius details amino acids 528 to 547 (20 residues), see Phobius details amino acids 554 to 573 (20 residues), see Phobius details PF04116: FA_hydroxylase" amino acids 93 to 226 (134 residues), 106.2 bits, see alignment E=1.9e-34 PF07947: YhhN" amino acids 389 to 574 (186 residues), 143.5 bits, see alignment E=6.2e-46

Best Hits

KEGG orthology group: None (inferred from 89% identity to vpe:Varpa_5280)

Predicted SEED Role

"Sterol desaturase-related protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (580 amino acids)

>GFF2093 Fatty acid hydroxylase family (carotene hydroxylase/sterol desaturase) (Variovorax sp. SCN45)
MRPGQIIVLATPVFFLLIAIEFAVGRARARRGTGQDTYRLADAVNSVGLGMLSQISAVLT
GLLRIGIYTAVYSAVALFPLEAARDFWTTWYGWLLALLFYDFCYYWLHRMGHESAVLWAA
HVVHHQSQHYNLSTALRQTSSGALFGWIFYLPMAVAGVPPLVFGVVALIDLLYQFWVHTE
QVGKLGWFDRWFCSPSNHRVHHAVNDPYLDRNYGGILIVWDRMFGTFREEGERCVYGTRG
ELRSWDPLWANAEVYWALAKDSWHAKSWADKLRVWLKPPGWRPADVAARFPKPAFDIARV
TRYEPEVSRGVQWFAGLQFLLLVGCAMVFLWFSDVTALPRAAVWLAALTASLWAIGGALQ
GRLTVTEVLLVEAAALATASSALGIGWLHYIFKPLALAIAIFFAARRAMASGAVTGFDGL
LLTGLVASLAGDVLLMGPQTLFVPGLVGFLLAHLAYIALFSIGVGMFPRRGVLAATLLIG
AGMYAFLWQGGLPAALRIPVGAYVVVIACMAAQAIGRAAVLRDADPSARWVAVGACFFML
SDSLLATNRFVTPLPLAALWVLGTYYTAQMLIVRNARPRG