Protein Info for GFF209 in Sphingobium sp. HT1-2

Annotation: Uncharacterized protein CC_3059

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 214 signal peptide" amino acids 25 to 27 (3 residues), see Phobius details amino acids 47 to 51 (5 residues), see Phobius details transmembrane" amino acids 28 to 46 (19 residues), see Phobius details amino acids 163 to 186 (24 residues), see Phobius details amino acids 194 to 213 (20 residues), see Phobius details PF03929: PepSY_TM" amino acids 10 to 183 (174 residues), 48.1 bits, see alignment E=1.5e-16 PF16357: PepSY_TM_like_2" amino acids 18 to 214 (197 residues), 266.8 bits, see alignment E=1.5e-83

Best Hits

KEGG orthology group: K09939, hypothetical protein (inferred from 88% identity to sjp:SJA_C1-09170)

Predicted SEED Role

"FIG019175: putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (214 amino acids)

>GFF209 Uncharacterized protein CC_3059 (Sphingobium sp. HT1-2)
MHAPARAQPKKKKSAKAFWLKQLHTWHWVSSAISLIGLLLFAFTGITLNHAADVEGSPRT
VEKSATLPAPLLKLVAADDAPDAKKPLPAPIAQWVEKEIGQSGAGEAEWSADEVYLALPR
PGGDGWVSIDRHDGKVTSEATSRGWVSYLNDLHKGRNAGTVWKWFIDIFAIACFLFALTG
LLLLQLHAAKRPSTWPLVAIGLALPALLAILFIH