Protein Info for GFF2082 in Xanthobacter sp. DMC5

Annotation: Ferrichrome outer membrane transporter/phage receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 728 signal peptide" amino acids 1 to 60 (60 residues), see Phobius details PF07715: Plug" amino acids 102 to 204 (103 residues), 73.5 bits, see alignment E=2e-24 TIGR01783: TonB-dependent siderophore receptor" amino acids 104 to 727 (624 residues), 330.6 bits, see alignment E=1.1e-102 PF00593: TonB_dep_Rec_b-barrel" amino acids 292 to 699 (408 residues), 200.6 bits, see alignment E=8.8e-63

Best Hits

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (728 amino acids)

>GFF2082 Ferrichrome outer membrane transporter/phage receptor (Xanthobacter sp. DMC5)
MPVFTPHPHDHRRRNKGSLGRKSRQSLAAKPFSTIALTARSLLATSALIVPVSFGMAQAQ
EAAPSVALPTVNVEGVAETAWGPVEGYVATRSGAGTKTDTPLIDTPRSVSVVTRQEMDDR
GVQNVVDAVSYTAGVLTGSYGYDPRFDDIYIRGFSVSSRGNFRDSLAQPSANFASWRTET
YGLERIDVIKGPASVLYGQTVPGGLINRISKMPVDTPFAEVEGQLGDPAWSQAAFDVGGR
ANADGSVLYRLTGVARAADGTVSYSTNNALYLAPAVTFQNETTRLTILGTVLDSRTPSNT
QYWQTPTMLTRIPMGTTYNAIQQTQEQIGYQLEHAFNDVWSAKQNVRYGHIDNHSMWMDA
NGVMNGPLISMTATNYIETVNSFQADNQLQAKFTTGPVEHKVLGGVDYLWLDSSYGMGDG
PAGDVNIFNPNVPNLLVMPAITSRDGAGLNQVGLYLQDQMAFGNGWRFLIGGRQDFASTS
QSSFGIETAGRDDQAFTWQAGLLYAFENGVSPYVSYATSFLPSINVDQSGQLLEPSSGEQ
YEAGVKYQPKGGRSFFTLSAYQITQNNYAVPDPVSFFYLPVGNVRVRGFEAEALVELAQG
LDLTAAYTFTQGRIINSLDVPTIGNTPPNMPAHIASLWAKYTVQDGDWKGFGVGGGIRYI
GPFWSDTNNLYKNGAQYPVDAALYYEKDNWNFQLNAKNVFGQQNALLNEGYWYWQQGRSV
IASVRYRW