Protein Info for PS417_01045 in Pseudomonas simiae WCS417

Annotation: RND transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 356 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 30 to 350 (321 residues), 235.1 bits, see alignment E=4.9e-74 PF16576: HlyD_D23" amino acids 53 to 258 (206 residues), 43.2 bits, see alignment E=4.4e-15 PF13533: Biotin_lipoyl_2" amino acids 60 to 102 (43 residues), 26.6 bits, see alignment 5.9e-10 PF13437: HlyD_3" amino acids 171 to 265 (95 residues), 33 bits, see alignment E=1.3e-11

Best Hits

KEGG orthology group: None (inferred from 94% identity to pfs:PFLU0233)

Predicted SEED Role

"Efflux membrane fusion protein, RND family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U5B0 at UniProt or InterPro

Protein Sequence (356 amino acids)

>PS417_01045 RND transporter (Pseudomonas simiae WCS417)
MKRLTGILAASLLLVACSKEDAPPEPVRPVLSMEVKAEDQENLGRFAGTIQARYESNLGF
RVPGRIARRVVDVGAEVEKGALLAVLDPTDQQNQLRSAQGDLARVQAQYINAQANARRQQ
ELFNRGVGAQAQLDIAQTDLKTTQATLDQAKASVNQANDQLRYAELRTDHAGIVTAWNAE
AGQVVSAGQQVVTLARPDIKEAVIDLPAGLAERLPPDVVFLVAGQLDPSVNTTAIVREIE
PQAQSATRTRRARLTLTETPPAFRLGTAISVTLSTAIAPRIEVPLSALQEVDGKTRIWLL
DTHSQTVQTRDISVISRDADSALLNDGVKPGERIVIAGVNSLKPGQKVKIDEDSPR