Protein Info for GFF2051 in Xanthobacter sp. DMC5

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 523 TIGR00150: tRNA threonylcarbamoyl adenosine modification protein YjeE" amino acids 19 to 145 (127 residues), 81 bits, see alignment E=3.7e-27 PF02367: TsaE" amino acids 20 to 138 (119 residues), 102.7 bits, see alignment E=1.4e-33 PF01636: APH" amino acids 191 to 444 (254 residues), 78.8 bits, see alignment E=5.5e-26

Best Hits

KEGG orthology group: K07102, (no description) (inferred from 83% identity to xau:Xaut_3297)

Predicted SEED Role

"TsaE protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA / COG3178: Predicted phosphotransferase related to Ser/Thr protein kinases" in subsystem YjeE

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (523 amino acids)

>GFF2051 hypothetical protein (Xanthobacter sp. DMC5)
MSIVLERLEGQPVACRVVLKDLAATSRLASLIASWFGGKDTITLTGDLGAGKTELARALI
RAFADDAGVDVPSPTFPILISYDFPRGRVVHADLYRIQEPDELDELGWDELRENALLMVE
WPERAEERLPADRLDVALYLAAGTRDAATLGPEARIAIVTGYGSFGPRLDRLMIAQSLIE
QSGFAEAAHRFLQGDASARSYSRLVLGDRSAIVMNAPRQPDGPPLKRGLPYSQLVHLAED
VKPFVAMDRALLAQGLSAPLIYSADLEAGILVLEDLGPEFVVAGTPPAPVPERYRLAVEV
LATLHSRPLPRTLNIAPRVERALPSYDVAAMLTEIDLMLDWYLPSRGIRLDGVVREEFRL
LWRSALNPAMAEPPTWVLRDYHSPNLIWLPQREGLRRIGLIDFQDAVMGPAAYDVVSLAQ
DARVDVPEELELELVRRYVAMRREADPTFDPRGFARTYALMGAQRASKILGIFTRLNDRD
GKPHYLRHLPRIRRYLARCLAHEELGSLRMWYEAVLPSKDLSA