Protein Info for GFF2044 in Variovorax sp. SCN45

Annotation: Efflux ABC transporter, permease protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 260 transmembrane" amino acids 18 to 40 (23 residues), see Phobius details amino acids 52 to 72 (21 residues), see Phobius details amino acids 113 to 132 (20 residues), see Phobius details amino acids 138 to 159 (22 residues), see Phobius details amino acids 198 to 217 (20 residues), see Phobius details amino acids 227 to 250 (24 residues), see Phobius details PF06182: ABC2_membrane_6" amino acids 30 to 259 (230 residues), 164.6 bits, see alignment E=1.6e-52

Best Hits

KEGG orthology group: K01992, ABC-2 type transport system permease protein (inferred from 90% identity to vap:Vapar_4687)

Predicted SEED Role

"ABC transporter permease protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (260 amino acids)

>GFF2044 Efflux ABC transporter, permease protein (Variovorax sp. SCN45)
MRLVAASLSGQARYPASALMLTTGQFLGTGIEVIAVWALFHRFGEVQGWQLGEVALFYGL
VNCMFAVADALGRGFDTLGTEFLRTGAFDRLLLRPRPVALQLMGHDFRISRAGRLLQGAL
VLVFATVQANIAWTPAAIGIALFALAGGAALFLGILVLQGTLSFWTVESLEIANVLTYGG
VQAAQYPLALYAQWFRRVLTFIVPLACVAYYPALAILGKPDPLGAPAWMGLVSPLAGFVF
LAAAFGVWRFGLRHYASTGS