Protein Info for GFF2038 in Sphingobium sp. HT1-2

Annotation: Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 401 PF00144: Beta-lactamase" amino acids 27 to 387 (361 residues), 216.8 bits, see alignment E=2.3e-68

Best Hits

KEGG orthology group: None (inferred from 76% identity to sch:Sphch_0583)

Predicted SEED Role

"Beta-lactamase class C and other penicillin binding proteins" in subsystem Beta-lactamase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (401 amino acids)

>GFF2038 Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily (Sphingobium sp. HT1-2)
MATAKVTDAAAARAAGMDPDRLDALVDHLDRTYVQSGKLPHMQMLVSRDEVPLLSVSRGQ
ARASGEPLQADALFRIASMTKPVTSVAFMRLVEQGKVALDDPVTDVLPEFADLRVGADGR
GRMTRPMRMIDLLRHTSGLTYGLQRQTPIDACYRELGLDEFQQKRSSDEFIAALASLPLE
FSPGERWNYGVSTDVLGVIVERLSGQDLETHFRQNIFDPLGMKDSFFTLPEDRTDRLTDA
WGLGEDGLRLRDRGAASSWRRKLRFRSGGGGLISSTADYHRFARMLLRGGELDGARLLQP
DTVAQMRSNHLPGGGDLASMSQAMFSEADYAGVGFGLGFAMTLANQQFYWGGVFSTYFFI
DPVERLIGLFMTQHLPSSTYPVRAELRAGIGAAIVTRRGQG