Protein Info for PS417_10380 in Pseudomonas simiae WCS417

Annotation: catalase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00199: Catalase
  • amino acids 5 to 385 (381 residues), 633.5 bits, E=1.4e-194
• PF06628: Catalase-rel
  • amino acids 413 to 473 (61 residues), 67.7 bits, E=8.1e-23

Best Hits

Swiss-Prot: 76% identical to CATA_ALIF1: Catalase (katA) from Aliivibrio fischeri (strain ATCC 700601 / ES114)

KEGG orthology group: K03781, catalase [EC: 1.11.1.6] (inferred from 88% identity to pfo:Pfl01_2262)

MetaCyc: 47% identical to CAT2 subunit (Arabidopsis thaliana col)
Catalase. [EC: 1.11.1.21, 1.11.1.6]

Predicted SEED Role

"Catalase (EC 1.11.1.6)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) (EC 1.11.1.6)

MetaCyc Pathways

• reactive oxygen species degradation (4/4 steps found)
• ethanol degradation IV (3/3 steps found)
• superoxide radicals degradation (2/2 steps found)
• methanol oxidation to formaldehyde IV (1/2 steps found)

KEGG Metabolic Maps

• Methane metabolism
• Tryptophan metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.6

Use Curated BLAST to search for 1.11.1.21 or 1.11.1.6

Sequence Analysis Tools

See U1THS6 at UniProt or InterPro

Protein Sequence (477 amino acids)

>PS417_10380 catalase (Pseudomonas simiae WCS417)
MKKLTTAAGAPVVDNNHSQTAGPRGPVLLQDVWLLEKLAHFDREVIPERRMHAKGSGAFG
RFTVTHDISRFTKADLFSHVGKTTDIFVRFSTVAGERGAADAERDIRGFAIKFYTEQGNW
DLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSARNNWDFWTLLPEALHQVTIVMSDR
GLPQSYRHMHGFGSHTFSFISPTNERFWVKFTWKTAQGIHNLTDEQASQVVGDDRESAQR
DLYTSIEEGRFPRWKLHVQIMPEAEAGTYPINPFDLTKVWPHRDYPLIEVGVLELNRNPD
NYFVDVEQAAFNPANVVPGISFSPDKMLQARLFAYGDAQRYRVGVNHHQIPVNAPRCPVN
SYHRDGQMRTDHNAGSTLGYEPNSHAQWMEQPDFREPPLALQGSAAHWNHREDTDYFSQP
GALFRLMSAAQQHALFANTARSIQGASSQAKERHIQHCTQADPAYGAGVARAIELLG