Protein Info for GFF2035 in Sphingobium sp. HT1-2

Annotation: Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 419 TIGR02091: glucose-1-phosphate adenylyltransferase" amino acids 13 to 389 (377 residues), 502.4 bits, see alignment E=3.7e-155 PF00483: NTP_transferase" amino acids 15 to 283 (269 residues), 203 bits, see alignment E=8.8e-64 PF24894: Hexapep_GlmU" amino acids 306 to 409 (104 residues), 133.9 bits, see alignment E=3.3e-43

Best Hits

Swiss-Prot: 77% identical to GLGC_RHILW: Glucose-1-phosphate adenylyltransferase (glgC) from Rhizobium leguminosarum bv. trifolii (strain WSM2304)

KEGG orthology group: K00975, glucose-1-phosphate adenylyltransferase [EC: 2.7.7.27] (inferred from 90% identity to sch:Sphch_0586)

MetaCyc: 56% identical to glucose-1-phosphate adenylyltransferase (Escherichia coli K-12 substr. MG1655)
Glucose-1-phosphate adenylyltransferase. [EC: 2.7.7.27]

Predicted SEED Role

"Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)" in subsystem Glycogen metabolism (EC 2.7.7.27)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.27

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (419 amino acids)

>GFF2035 Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27) (Sphingobium sp. HT1-2)
MQQRNQPIARDAMAYVLAGGRGSRLAELTDRRAKPAVHFGGKARIIDFALSNALNSGIRR
IGVATQYKAHSLIRHLQRGWNFLRPERNESFDILPASQRISESQWYEGTADAVFQNIDII
ESYAPEYMVILAGDHVYKMDYELMLQQHVDSGADVTVGCLEVPRMEAVGFGVMHVDEADV
ITAFVEKPKDPPAIPGQPDMALASMGIYVFRTRFLIEQLWRDADDKNSKRDFGGDIIPHI
VKHGKAVAHRFSSSCVRAESELVPYWRDVGTIDAYWQANIDLTDVVPSLDLYDRSWPLWT
YSEVTPPAKFVHNEDGRRGSATSSLVAGGCIVSGSSLHRSLLFSEVRTHSFSSITESVIM
PNCVIGRGARLHKCVVDSGISIPPGLIIGEDPAFDAQHFRRTDSGICLVTQPMIDRLVA