Protein Info for GFF2035 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Xanthosine permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 418 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 42 to 62 (21 residues), see Phobius details amino acids 71 to 89 (19 residues), see Phobius details amino acids 95 to 116 (22 residues), see Phobius details amino acids 135 to 154 (20 residues), see Phobius details amino acids 160 to 179 (20 residues), see Phobius details amino acids 211 to 232 (22 residues), see Phobius details amino acids 254 to 275 (22 residues), see Phobius details amino acids 282 to 300 (19 residues), see Phobius details amino acids 306 to 327 (22 residues), see Phobius details amino acids 347 to 369 (23 residues), see Phobius details amino acids 382 to 402 (21 residues), see Phobius details PF03825: Nuc_H_symport" amino acids 1 to 406 (406 residues), 613.4 bits, see alignment E=4e-188 TIGR00889: nucleoside transporter" amino acids 1 to 418 (418 residues), 706.9 bits, see alignment E=4.7e-217 PF12832: MFS_1_like" amino acids 6 to 373 (368 residues), 95.1 bits, see alignment E=9.5e-31 PF01306: LacY_symp" amino acids 9 to 402 (394 residues), 34.2 bits, see alignment E=2.7e-12 PF07690: MFS_1" amino acids 254 to 412 (159 residues), 46.4 bits, see alignment E=5.6e-16

Best Hits

Swiss-Prot: 89% identical to XAPB_ECOLI: Xanthosine permease (xapB) from Escherichia coli (strain K12)

KEGG orthology group: K11537, MFS transporter, NHS family, xanthosine permease (inferred from 100% identity to sew:SeSA_A2656)

MetaCyc: 89% identical to xanthosine:H+ symporter XapB (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-31

Predicted SEED Role

"Xanthosine permease" in subsystem Xanthosine utilization (xap region)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (418 amino acids)

>GFF2035 Xanthosine permease (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MGITSRLKVMSFLQYFIWGSWLVTLGSYMINTLDFTGANVGMVYSSKGLAAIIMPGIMGI
IADKWLRAERAYMLCHLVCAGALLYATTVTDPQTMFWVMLVNAMAYMPTIALSNSVSYSC
LAKAGQDPVTSFPPVRVFGTIGFIVAMWTVSLMGLELSSAQLYIASGASLLLALYALTLP
KIPVAEKKANTTLASKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFAR
NPEFADSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMLAWTLRFGFFAF
GDPSPFGFVLLLLSMIVYGCAFDFFNISGSVFVEQEVDSSIRASAQGLFMTMVNGVGAWI
GSLLSGMAVDYFSIDGVKDWQTIWLVFAAYALALAVIFALFFKYQHHPEKLSTKSLAH