Protein Info for PS417_10345 in Pseudomonas simiae WCS417

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 408 signal peptide" amino acids 1 to 42 (42 residues), see Phobius details transmembrane" amino acids 54 to 76 (23 residues), see Phobius details amino acids 88 to 106 (19 residues), see Phobius details amino acids 115 to 133 (19 residues), see Phobius details amino acids 145 to 166 (22 residues), see Phobius details amino acids 174 to 196 (23 residues), see Phobius details amino acids 225 to 245 (21 residues), see Phobius details amino acids 261 to 281 (21 residues), see Phobius details amino acids 291 to 309 (19 residues), see Phobius details amino acids 314 to 338 (25 residues), see Phobius details amino acids 350 to 371 (22 residues), see Phobius details amino acids 382 to 399 (18 residues), see Phobius details PF07690: MFS_1" amino acids 30 to 291 (262 residues), 124.4 bits, see alignment E=8e-40 amino acids 270 to 400 (131 residues), 34.3 bits, see alignment E=1.9e-12 PF06779: MFS_4" amino acids 49 to 394 (346 residues), 28.9 bits, see alignment E=1.2e-10 PF00083: Sugar_tr" amino acids 55 to 199 (145 residues), 62.3 bits, see alignment E=6.5e-21

Best Hits

KEGG orthology group: None (inferred from 74% identity to pfo:Pfl01_5712)

Predicted SEED Role

"4-hydroxybenzoate transporter" in subsystem Cinnamic Acid Degradation or Gentisare degradation or Phenylpropanoid compound degradation or Salicylate and gentisate catabolism or p-Hydroxybenzoate degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See U1UN26 at UniProt or InterPro

Protein Sequence (408 amino acids)

>PS417_10345 MFS transporter (Pseudomonas simiae WCS417)
MSRQAISAATPSISSRRAAWTVVGLCLLFNVIDGLDAMAMAFTASRVAAQWSLGAAQVGL
LLSASLVGMACGSLGIAPMANRHGRRRVLLAGLMLSGVAMVLSFWSQGYCTLLCMRLLTG
MGVGAVLVGANVLTHDHAPPRYRNLAIALQSVAFALGATLGGVLAHQLNDSLGWRYVFLA
GGCLTLLVGFVGMLWLRESTSRLALTAGRPGLGYRDLFSQGRWPSTCALACVGFLLMFGF
YFVMSWTPMLLTHSGFSARHGITGGMLLTVGGMFGALLLGLGANRWGCNRLLCMCLLLNA
VMMLLMVTATRIPILAIATGFTAGLLLYAAIAALFVLAPQAFASPERTRGVGVVLATGRL
GAIVSPTFAGVLLDAQWRPQDLFTVYAGSQLLAALLIWRSHRATPEAG