Protein Info for GFF2019 in Xanthobacter sp. DMC5

Annotation: Cytochrome bd-I ubiquinol oxidase subunit 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 525 transmembrane" amino acids 18 to 43 (26 residues), see Phobius details amino acids 55 to 76 (22 residues), see Phobius details amino acids 94 to 117 (24 residues), see Phobius details amino acids 129 to 148 (20 residues), see Phobius details amino acids 188 to 209 (22 residues), see Phobius details amino acids 221 to 239 (19 residues), see Phobius details amino acids 393 to 415 (23 residues), see Phobius details amino acids 427 to 448 (22 residues), see Phobius details amino acids 469 to 493 (25 residues), see Phobius details PF01654: Cyt_bd_oxida_I" amino acids 8 to 506 (499 residues), 583 bits, see alignment E=1.4e-179

Best Hits

Swiss-Prot: 59% identical to CYDA_SHIFL: Cytochrome bd-I ubiquinol oxidase subunit 1 (cydA) from Shigella flexneri

KEGG orthology group: K00425, cytochrome bd-I oxidase subunit I [EC: 1.10.3.-] (inferred from 79% identity to atu:Atu4091)

MetaCyc: 59% identical to cytochrome bd-I subunit 1 (Escherichia coli K-12 substr. MG1655)
RXN0-5266 [EC: 7.1.1.7]; 1.11.1.- [EC: 7.1.1.7]; 1.11.1.- [EC: 7.1.1.7]

Predicted SEED Role

"Cytochrome d ubiquinol oxidase subunit I (EC 1.10.3.-)" in subsystem Terminal cytochrome d ubiquinol oxidases or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (525 amino acids)

>GFF2019 Cytochrome bd-I ubiquinol oxidase subunit 1 (Xanthobacter sp. DMC5)
MILDTVDLSRLQFAVTALYHFLFVPLTLGLSVLLAIMETVYVMTGRPIWRQMTKFWGTLF
GINFVLGVATGIVMEFQFGMNWSYYSHYVGDIFGAPLAIEGLMAFFLEATFVGLFFFGWD
RLSKVGHLVTTYAVAMGSNLSALWILIANGWMQNPTGAAFNPQTMRMEVSDFYAVLFNPV
AQAKFVHTVSAGYVTASFFVLGVSAWYLLKGRHIDLAKRSMTVAASFGLAASLSVVVLGD
ESGYLDGEHQKMKLAAIEAMWETEPAPAGFTIVGLPDQAARETRFAVRVPWVLGLIATRT
LTTQIPGIEELVGHAETRIKSGIVAFDALQQIRAAGSSAAIAPAVKQAFEDNGGNLGYAL
LLKRYVDDPRKATAAEVNQAAWDTVPNVPTLFWSFRVMVGLGFFFIAFTAFVFYLSARRR
LDRSRTLLWIAVLAIPLPWIAAELGWVVAEVGRQPWIIEGVLPTAAAVSSLGAGTVLATL
AGFAAIYTVLIVVEMTLMFRAIRKGPEPDEAPEARLIPPAFAAAE