Protein Info for GFF2007 in Xanthobacter sp. DMC5

Annotation: Proline/betaine transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 445 transmembrane" amino acids 24 to 46 (23 residues), see Phobius details amino acids 60 to 83 (24 residues), see Phobius details amino acids 95 to 115 (21 residues), see Phobius details amino acids 122 to 143 (22 residues), see Phobius details amino acids 163 to 185 (23 residues), see Phobius details amino acids 198 to 216 (19 residues), see Phobius details amino acids 256 to 275 (20 residues), see Phobius details amino acids 295 to 315 (21 residues), see Phobius details amino acids 325 to 343 (19 residues), see Phobius details amino acids 352 to 374 (23 residues), see Phobius details amino acids 387 to 409 (23 residues), see Phobius details amino acids 417 to 437 (21 residues), see Phobius details PF00083: Sugar_tr" amino acids 23 to 443 (421 residues), 72.8 bits, see alignment E=2.7e-24 PF07690: MFS_1" amino acids 53 to 400 (348 residues), 77.4 bits, see alignment E=9.9e-26

Best Hits

KEGG orthology group: None (inferred from 64% identity to gmc:GY4MC1_2419)

Predicted SEED Role

"L-Proline/Glycine betaine transporter ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (445 amino acids)

>GFF2007 Proline/betaine transporter (Xanthobacter sp. DMC5)
MSVQDTSLAPAAIAVGSRQRNSAIIASVLGWSLDLFDLFILLYVAPVVGQLFFPSTHPTW
SLAAVYASFAVTLLMRPIGSALFGHYADVHGRKGAMLVAITGVGLSTAAFGLLPTIHQVG
AIAPVIFLLLRLVQGVFVGGVVASTHTIGTESVPANWRGFMSGLVGGGGAGIGALLASIV
FLITSTLFPGEAFAETGWRVMFFSGLLSSFLGWFIFRNLEESPYWKEMQKQKAAKKAAGT
ASQAPLKALFAGGYRNVLLVNLLITIGGGAGYYLTSGYMPTFLKLINQLPNQTSSYILMA
CSVSALVSAVLVGALSDIIGRKKTFMLVGVAAIILLPTFYLGMAKATDLSTIVLYALGIA
FMGNAGYAPVLIFLNERFPTAMRASGTGLSWNIGFAIGGMMPTFVSLASATPSDLPMSLS
IFAVAVFALYLVGTLIIPETKGNFR