Protein Info for GFF1987 in Xanthobacter sp. DMC5

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 530 PF00571: CBS" amino acids 66 to 118 (53 residues), 18.8 bits, see alignment 2.5e-07 amino acids 129 to 189 (61 residues), 23.2 bits, see alignment E=1.1e-08 PF03445: DUF294" amino acids 214 to 342 (129 residues), 142.3 bits, see alignment E=1.4e-45 PF10335: DUF294_C" amino acids 384 to 525 (142 residues), 145.4 bits, see alignment E=1.7e-46

Best Hits

KEGG orthology group: K07182, CBS domain-containing protein (inferred from 77% identity to xau:Xaut_2430)

Predicted SEED Role

"Predicted signal-transduction protein containing cAMP-binding and CBS domains" in subsystem cAMP signaling in bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (530 amino acids)

>GFF1987 hypothetical protein (Xanthobacter sp. DMC5)
MPRPDPMTGPPNGDRREDEPRAATARGTDPHGPEDAPAASGPPAPGRASPSERDRRELVS
LMTSRVRDVYLRKPFFVDGSTDLVSLCRDLSARRLSEAVVRDGDRIGIFTTTDLRDALTR
DTPPSALMVREVATFEPWCIAPDAELFEALILMLRHRIHRLLVREGGGRAAGGDGILGVL
GQLDLMAFVANHSHLIALEAAQAGSLDELKAAARQIDSMVAVLSADGVRVEVIAALVGEL
NAQIFRRLWELLAPEELRANSCLIVMGSEGRGEQIIKTDQDNGLILRDGFAFAGLDDVTA
RFTAALIDFGYPPCPGGVMLSRPTWCQPLSAFKETLKDWIHGGVQDGPMNLAIFLDAVAV
AGDAALAAAARAHVDFLMMGDHGYFARFAQAVDRFGESGSWWSRLPGLTGRGAAEVDLKK
LGIFPLVHGVRALALEHRITALGTADRLAALVAAGHMDEGFARDLTDALRLFMGMKLSSN
LRQIADGRPPSNALRLADLGTLDRQALKEALAIVRGFKQWLSRHYRFDAL