Protein Info for GFF1986 in Xanthobacter sp. DMC5

Annotation: Cation/acetate symporter ActP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 581 signal peptide" amino acids 12 to 12 (1 residues), see Phobius details transmembrane" amino acids 13 to 32 (20 residues), see Phobius details amino acids 46 to 67 (22 residues), see Phobius details amino acids 89 to 110 (22 residues), see Phobius details amino acids 116 to 135 (20 residues), see Phobius details amino acids 161 to 182 (22 residues), see Phobius details amino acids 192 to 211 (20 residues), see Phobius details amino acids 223 to 243 (21 residues), see Phobius details amino acids 291 to 314 (24 residues), see Phobius details amino acids 331 to 353 (23 residues), see Phobius details amino acids 385 to 413 (29 residues), see Phobius details amino acids 434 to 453 (20 residues), see Phobius details amino acids 458 to 482 (25 residues), see Phobius details amino acids 490 to 512 (23 residues), see Phobius details amino acids 529 to 549 (21 residues), see Phobius details TIGR00813: transporter, solute:sodium symporter (SSS) family" amino acids 76 to 498 (423 residues), 195.6 bits, see alignment E=7.8e-62 PF00474: SSF" amino acids 76 to 498 (423 residues), 384 bits, see alignment E=4.2e-119

Best Hits

KEGG orthology group: K14393, cation/acetate symporter (inferred from 90% identity to xau:Xaut_2431)

Predicted SEED Role

"Acetate permease ActP (cation/acetate symporter)" in subsystem Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (581 amino acids)

>GFF1986 Cation/acetate symporter ActP (Xanthobacter sp. DMC5)
VTATLPTSYARRALAIGAMAAVVLAPTLVLAAGGDLGQADKQSTNWTAITMFAVFVMGTL
YITKWAAAKTKSAADFYTAGGGITGFQNGLAIAGDYMSAASFLGISAAVMTSGYDGLIYS
IGFLVGWPILTFLMAERLRNLGKFTFADVAAFRFAQTPVRVFAASGTLVVVAFYLIAQMV
GAGQLIKLLFGLDYWIAVVIVGALMMVYVLFGGMTATTWVQIIKACLLLGGASFMAFMVM
WRYGFSPEKMFAAAVEVKTNLAAAKPGTTPQAAAAAGQAIMGPGTFIKDPISAISFGMAL
MFGTAGLPHILMRFFTVPSAKEARKSVMWATGWIGYFYLLTFIIGFGAITFVLTNPEFLD
AKGGLIGGSNMAAVHLAHAVGGNVFLGFISAVAFATILAVVAGLTLSGASAVSHDLYSTV
IKKGKADSASELKVSRATTVALGILAVLLGIAFEKQNIAFMVSLAFAVAASANFPVLFMS
VLWKDCTTKGAVIGGFLGLLSSVLLTVLSPSVWEATLGNPAGSAPFPYTSPALFSMTLGF
VGIWLFSILDNSQRAKIDRAGFPAQEVRSETGIGASEASGH