Protein Info for PS417_01000 in Pseudomonas simiae WCS417

Annotation: Fis family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 PF00158: Sigma54_activat" amino acids 33 to 191 (159 residues), 179.7 bits, see alignment E=4.1e-57 PF14532: Sigma54_activ_2" amino acids 36 to 199 (164 residues), 78.4 bits, see alignment E=6.6e-26

Best Hits

KEGG orthology group: None (inferred from 96% identity to pfs:PFLU0214)

Predicted SEED Role

"Functional role page for Anaerobic nitric oxide reductase transcription regulator NorR" in subsystem Nitrosative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UB59 at UniProt or InterPro

Protein Sequence (308 amino acids)

>PS417_01000 Fis family transcriptional regulator (Pseudomonas simiae WCS417)
MSLHETYGQPLLTFPDAEKSPLSIRAKALVFVDPRSRQLREELESLAPRALPVLIRGETG
SGKELLARHIHRGSDRTGLFVSVNCGAISPTYADAELFGYAAGSHSGTASSRAGWFGSAN
GGTLYLDEIGDLPLPIQVKLLAALENHEVTRVGAHQPSPVDVRLVAATSIDLAQAVAAGK
FHERLFHYLSEGRLDLPALRERVGDILSLAEYFLGIYSQRLDLPVPLISDAAQRVLEHHS
WPGNTRELENVIHFALLVSSGDEILPEHLNLPVAGSPLEQVQRIFHSASPAEQETLRKFL
HEQNGIST