Protein Info for GFF1979 in Xanthobacter sp. DMC5

Annotation: Sulfite reductase [ferredoxin]

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 586 TIGR02435: precorrin-3B synthase" amino acids 103 to 506 (404 residues), 414.1 bits, see alignment E=2.8e-128 PF03460: NIR_SIR_ferr" amino acids 112 to 170 (59 residues), 56.2 bits, see alignment 2.3e-19 amino acids 364 to 430 (67 residues), 75.4 bits, see alignment E=2.4e-25 PF01077: NIR_SIR" amino acids 182 to 340 (159 residues), 108.3 bits, see alignment E=2.7e-35 amino acids 444 to 575 (132 residues), 58.8 bits, see alignment E=4.5e-20

Best Hits

KEGG orthology group: K00366, ferredoxin-nitrite reductase [EC: 1.7.7.1] (inferred from 85% identity to xau:Xaut_2499)

Predicted SEED Role

"Ferredoxin--nitrite reductase (EC 1.7.7.1)" in subsystem Nitrate and nitrite ammonification (EC 1.7.7.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.7.7.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (586 amino acids)

>GFF1979 Sulfite reductase [ferredoxin] (Xanthobacter sp. DMC5)
MGADFTLDQKLYLEGFVSGAKAVQIARGAAPATAAQPVAEMTGPDAASHRAMARTEAEGR
KLTPEEKAKREELGLDAYDRMRHAAREGTFPKGPDVLRWKYHGLFYVAPAQDSFMCRMRI
PGGILTHWQFRGVADIAERHGGGFTDITTRANLQIREIPPTDGIAVLEGLVSLGLTAKGS
GADNIRNVTGTPTAGIDRQELLDTRPLASAWHHYILNSRDMYGLPRKFNVAFDGAGTIGA
LEDTNDIGFQAVEVMDGFGIAPGVWLRLVLGGITGHKDFARDTGIVVRPEEAVDVAATIV
RAFIDTGDRTDRKKARLKYVLDSLGFDGFLKLVEAKLGRPFTRLAAEAVKPRAEPDRLAH
LGVHPQKQAGLNYVGIATPVGRMSATQMRGLADISARFGDGDIRLTVWQNLLISGVADAD
IAAVTDAVEALGLSTKATPLQAGIVACTGAKGCRFAAADTKGTARAILAHCEERVALDGP
VNIHVTGCHNSCAQHYIGDIGLIGARVPVNDDGDTVDGYHILVGGGFGSAAAIARELYQN
VPAEDAPAVVERLLKSWVAHRAKGETFADFTRRLDPDALKALAAAA