Protein Info for GFF1978 in Xanthobacter sp. DMC5
Annotation: Nitrite reductase [NAD(P)H]
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00362, nitrite reductase (NAD(P)H) large subunit [EC: 1.7.1.4] (inferred from 85% identity to xau:Xaut_2500)Predicted SEED Role
"Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)" in subsystem Nitrate and nitrite ammonification (EC 1.7.1.4)
MetaCyc Pathways
- alkylnitronates degradation (2/2 steps found)
- nitrate reduction V (assimilatory) (1/2 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 1.7.1.4
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (404 amino acids)
>GFF1978 Nitrite reductase [NAD(P)H] (Xanthobacter sp. DMC5) VSEPLLVIGNGMAAAKLCEELTRRALGRHAVAVIGAEPHLAYNRVLLSEVLAGHMTAAEA EMKPATWWRERGVTLQYGTPAAAIDRAAREVILADGRRLPFGKLVLATGSHPIRLPLPGM DLPGVHTFRDLDDVEALLAAAAVPGTRAVVIGGGLLGIEAAAGLAGAGVETRLVHLQDRL MERQLDAAAGAFLKRAVEAKGIEVLLGAASEAIEGDARVTGLRLKDGRVIPADILVVACG VTPNADLARAAGLDVKRGIVVDDTLAASDPDIFAIGECAEHRGMTYGLVAPAYEQAGVLA RRLAGEDARYEGSVVSTNLKVSGVPVFSAGDVTGGAGTEDIVLTDRGLGVYRRLIVKDGR LAGAVLFGDTADGLFYLDLITSRTPIAAMRTELAFGRDAVAAAA