Protein Info for GFF1964 in Sphingobium sp. HT1-2

Annotation: Twin-arginine translocation protein TatA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 79 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details signal peptide" amino acids 26 to 29 (4 residues), see Phobius details TIGR01411: twin arginine-targeting protein translocase, TatA/E family" amino acids 3 to 48 (46 residues), 63.3 bits, see alignment E=6.1e-22 PF02416: TatA_B_E" amino acids 5 to 49 (45 residues), 32.4 bits, see alignment E=2.1e-12

Best Hits

Swiss-Prot: 62% identical to TATA_AZOC5: Sec-independent protein translocase protein TatA (tatA) from Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)

KEGG orthology group: K03116, sec-independent protein translocase protein TatA (inferred from 95% identity to sch:Sphch_1440)

Predicted SEED Role

"Twin-arginine translocation protein TatA" in subsystem Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related or Twin-arginine translocation system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (79 amino acids)

>GFF1964 Twin-arginine translocation protein TatA (Sphingobium sp. HT1-2)
MGSFSLMHWVIVLLVVMLLFGGGRISGLMGDVAKGIKSFKKGMADDEDDATPAKPATRIE
GHRVPEQDAPSATEEKTKA