Protein Info for GFF1963 in Xanthobacter sp. DMC5

Annotation: Tol-Pal system protein TolB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 899 PF07676: PD40" amino acids 513 to 543 (31 residues), 18.9 bits, see alignment (E = 1.2e-07) amino acids 569 to 592 (24 residues), 20.7 bits, see alignment (E = 3.2e-08) TIGR01965: VCBS repeat" amino acids 674 to 766 (93 residues), 37.9 bits, see alignment E=8e-14

Best Hits

Predicted SEED Role

"tolB protein precursor, periplasmic protein involved in the tonb-independent uptake of group A colicins" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (899 amino acids)

>GFF1963 Tol-Pal system protein TolB (Xanthobacter sp. DMC5)
MATKTKAPAFGGLDRTKTLAENTVNAGPVVLDSNVTLKNPDGTGFQGGSLTVTLPNALLS
EHLSIAEVGGITLHTDSVTGETAVFYNGVQIGTEILLNGGLGVKFDHPVSDAAATALARA
FAYSTTTNQPSGTARAVTFTATDAEQSITTATMKITVKPENDAPVVSSLGPMSSQTPGSI
TSGFVIDGDAQVINPDPSGFKGGKLTVHLANATTTDQLYLSDGPWTITGTKVYLYGNLVG
TLSTNGAAGHDLVLTFKGNSFIPDEQMSALLHQVSYRSTASTPSTQPRDVTFTITDAEKS
SVSTHVTLSFENHTPSILASSPDGGISVISVGAVGQHANNLSSNPVVSPDGTEVAFLSTA
SSLLQVPTNVSIPAFSSPQVLVKNLHTGEVTLASSSATGDVGNQASTANIIFTQDGSKVE
FYSKASNLVPGDTNGTSDIFVKDIATGAISRIDPNDPNNQDIVNGFKAISSDGSKIVFDG
AGIGSPHSIFIQDVATGDVTFVCYGNVYNQNLAFSPDGTKIAFLSYPQDVSPGSNPGNMQ
LYVKDLATGQLTVESSDSAGHVGNSATTEAFSFSPDGTKIAFTSYSTNLVPGQGFNGIFI
KDLQTGAITELTVDASSYSSHPVFTPDGAHLIFTSSDIGPTYGGSILMASLPATSVTSAT
LTEDAARKTLNAAGTFYFADADAKDTHAVSVAAPDGALGTLSAKVVSDMNGTGAVVWSYV
VDETKVEPLAAGQTKVETFALTLDDHHGGTVTQNVSVTLTGTGGAAPMVASFALAPETTA
AAAPVSGPELWASAMASLSGVSEASPQLFDVLEKRAAALESAHAHGPAGAFEGAGAEIAH
LAAQIDPAVTHVLETLWSDLSGHGAGTASAHQIADGVEAIATHLRDALHPGHAGDPLLV