Protein Info for GFF1960 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Cell division protein FtsH (EC 3.4.24.-)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 766 PF07728: AAA_5" amino acids 294 to 426 (133 residues), 25.1 bits, see alignment E=1.2e-08 PF00004: AAA" amino acids 295 to 432 (138 residues), 53.8 bits, see alignment E=2.2e-17 amino acids 559 to 681 (123 residues), 99 bits, see alignment E=2.2e-31

Best Hits

KEGG orthology group: None (inferred from 78% identity to vpe:Varpa_0175)

Predicted SEED Role

"Cell division protein FtsH (EC 3.4.24.-)" in subsystem Bacterial Cell Division (EC 3.4.24.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (766 amino acids)

>GFF1960 Cell division protein FtsH (EC 3.4.24.-) (Hydrogenophaga sp. GW460-11-11-14-LB1)
VPHGLRQAPVLDLMCSHFVLTLAARQGPRFNVRRDLNTLLSLAGRHLVWPHTVLLRLREF
LARRCKDNELWSGHDGLTTNAFMERYGVWRGPYEEGTLFFYLDEYAKESPKDLLSVLAVT
GEWLSHSLKKQSTLVEKNIDALASLLQLNRAERALLLYGTLARYQRDLRSILVEFKVNNA
PEAYAAIADVAGVKASEVGEALRAGSRLERIGMVENLISEHNITDLADLMKVSEKLPPVL
MREYRTQSELMAVFTRPAARSALTPKDFDYVGEDVRLLCGLLREAVARKELGVNVLLYGP
PGTGKTELARVVAQAAGLELFEVEYADRDGNALSGRDRYRSLQIAQVFLKGTAHSALLFD
EVEDVFPPISSEAAQIMARAEHVAAAHTGSVSGKAWVNQILETNAVPTLWVTNRIEQIDP
AFRRRFAYHLELKSPPPGAREQLVRKTLEGAPVSDGLVARLTERKGLTPAQIRTALRFAQ
LAGQPAPRRGGKARATEAPVLDELIERQLKNADLALGRKPDLVQRPSATQYSLDMLNVES
RYELPRVIAALKARGHGCLCFHGAPGTGKTALAEHMAQQLDRPLMIRRASDLVSKFVGET
EQQMAAMFREAEAEKAVLLLDEADSFLQDRRGAQRTYEVTEVNEMLQGMERFAGIFICTT
NLMDSIDQAALRRFTFKIRFKPLTARQRETMFVVEALGGDAARLSPELATRLAKLEQLCP
GDFAAVKRQVEILAEALAPEEFMAQLEAEHRIKPEVREARPMGFTH