Protein Info for GFF194 in Xanthobacter sp. DMC5

Annotation: Glutathione transport system permease protein GsiC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 314 transmembrane" amino acids 9 to 30 (22 residues), see Phobius details amino acids 99 to 123 (25 residues), see Phobius details amino acids 135 to 159 (25 residues), see Phobius details amino acids 179 to 198 (20 residues), see Phobius details amino acids 238 to 261 (24 residues), see Phobius details amino acids 281 to 303 (23 residues), see Phobius details PF19300: BPD_transp_1_N" amino acids 2 to 76 (75 residues), 29.9 bits, see alignment E=5.5e-11 PF00528: BPD_transp_1" amino acids 113 to 313 (201 residues), 142.7 bits, see alignment E=1.1e-45

Best Hits

Swiss-Prot: 41% identical to GSIC_SALTY: Glutathione transport system permease protein GsiC (gsiC) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K02033, peptide/nickel transport system permease protein (inferred from 91% identity to xau:Xaut_3380)

MetaCyc: 41% identical to glutathione ABC transporter membrane subunit GsiC (Escherichia coli K-12 substr. MG1655)
RXN0-11 [EC: 7.4.2.10]

Predicted SEED Role

"Dipeptide transport system permease protein DppB (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) (TC 3.A.1.5.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (314 amino acids)

>GFF194 Glutathione transport system permease protein GsiC (Xanthobacter sp. DMC5)
VLVYVLRRIVYVIPIVVSVALVCFLLVHITPGDPLVAVLPPDASAELAAQMRAAYGFDQP
LPVQFGIWIWKALHGNLGTSIATGRPVLSEVTAAVGNTFILAVTAAFIGFVMGAFFGLIA
GYFRNTWVDKLATSIAVAGVSVPHYWLGMVLVIIFSVWLNWLPAVGMGPGGWAWNWEHLR
FLILPAVTMSVIPMGIVTRTVRALTGDILSQDFVEALRSKGLRETQVFRHVVKNALPTAI
AVMGLQLGYLLGGSILIETVFSWPGTGFLLNSAIFQRDLPLLQGTILVLALFFVFLNLVV
DIAQAAIDPRIKRA