Protein Info for GFF1925 in Sphingobium sp. HT1-2

Annotation: Predicted D-glucarate or D-galactorate regulator, GntR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 225 PF00392: GntR" amino acids 7 to 69 (63 residues), 64.8 bits, see alignment E=4.4e-22 PF07729: FCD" amino acids 93 to 216 (124 residues), 84.8 bits, see alignment E=7e-28

Best Hits

KEGG orthology group: None (inferred from 72% identity to cak:Caul_2069)

Predicted SEED Role

"Predicted D-glucarate or D-galactorate regulator, GntR family" in subsystem D-galactarate, D-glucarate and D-glycerate catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (225 amino acids)

>GFF1925 Predicted D-glucarate or D-galactorate regulator, GntR family (Sphingobium sp. HT1-2)
MNQARLSDHAYAGIVEIINDQDLAVGDRLPSEAALAERFGVSRAIVREALVRLASDGITE
ARRGAGSFVKSRPSQRLAAFMPATELPATLGSYEVRFVLEAEAARLAATRRSPIEMAHVE
EGMEMLRTALLSSEPAHAEDMELHRRIAEATGNPAFLIAFDALHADVDKVMRAGVDISRS
RPPEVIATMLREHEQIVAAIRAQDAEGAALAMRWHLWEGRRRLMP