Protein Info for GFF1924 in Variovorax sp. SCN45

Annotation: Aliphatic sulfonate monooxygenase family, FMNH2- or F420-dependent

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 373 PF00296: Bac_luciferase" amino acids 28 to 334 (307 residues), 246.9 bits, see alignment E=1.7e-77

Best Hits

Swiss-Prot: 36% identical to SSUD_ACIAC: Alkanesulfonate monooxygenase (ssuD) from Acidovorax citrulli (strain AAC00-1)

KEGG orthology group: K04091, alkanesulfonate monooxygenase [EC: 1.14.14.5] (inferred from 97% identity to vap:Vapar_3871)

Predicted SEED Role

"Alkanesulfonate monooxygenase (EC 1.14.14.5)" in subsystem Alkanesulfonate assimilation or Alkanesulfonates Utilization (EC 1.14.14.5)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.14.14.5

Use Curated BLAST to search for 1.14.14.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (373 amino acids)

>GFF1924 Aliphatic sulfonate monooxygenase family, FMNH2- or F420-dependent (Variovorax sp. SCN45)
MSQPQQDGAVEFIGMIQGQKVSEIHAAKGPALDRDYVRAFAQAHETAGFDRVLVPHHSTG
PDATLTVAHAASVTERIHFMLAHRPGFVAPTLAARQFASLDQFSGGRLAVHYISGGSDEE
QRRDGDWLDHDQRYARTDEYLDVLHKVWTAERPFDHEGAHYRFQNAFSEVKPLQTRNGKP
HVPVYFGGASQAAIPVAGKYADVYALWGESLDQARELTTRVRAEAAKHGRSVRFSVSFRP
ILAQTEEAAWARAENILAETKRLRVVQGYNRGGPQQSEGAKRLLAAAEKGSRLDKRLWTA
VAQEIGGRSNSTALVGTPEQVADALLDYYDLGVTTFLIRGFDPLEDALDYGRELIPRTRE
LVAQRAASIRKAA