Protein Info for GFF192 in Xanthobacter sp. DMC5

Annotation: Vitamin B12 import ATP-binding protein BtuD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 353 PF00005: ABC_tran" amino acids 44 to 192 (149 residues), 118.4 bits, see alignment E=3.8e-38 TIGR01727: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain" amino acids 242 to 322 (81 residues), 79.8 bits, see alignment E=6.1e-27 PF08352: oligo_HPY" amino acids 244 to 309 (66 residues), 73.9 bits, see alignment E=1.1e-24

Best Hits

Swiss-Prot: 50% identical to Y3404_BRUSU: Putative peptide import ATP-binding protein BRA0404/BS1330_II0401 (BRA0404) from Brucella suis biovar 1 (strain 1330)

KEGG orthology group: K02032, peptide/nickel transport system ATP-binding protein (inferred from 84% identity to xau:Xaut_3378)

Predicted SEED Role

"Oligopeptide transport ATP-binding protein OppF (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) (TC 3.A.1.5.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (353 amino acids)

>GFF192 Vitamin B12 import ATP-binding protein BtuD (Xanthobacter sp. DMC5)
LSTIEPLEDLGGPAQPLLAVNSLTKHFPIGGGLFAEKKTVRAVDDVSFTVAKGETLGIVG
ESGCGKSTTARLLMHLMPRTSGEILFDGQVVGYSLSVREFRRGMQMVFQDSYASLNPRLT
IEDSIAFGPKVHGVSDKEARALARELMGKVGLRPEVFANRYPHEVSGGQRQRVNIARALA
LKPRLVILDEAVSALDKSVEAQVLNLLTDLKHEFGLTYVFISHDLNVVRYISDRVLVMYL
GQVVEVGPVDQVWEAPAHPYTRALLAAMPALDPDKRTETPPLSGDPPNPIDPPAGCRFHT
RCSFAEEVCGRVGPALSPATPGDTAPDAHLAACHMVIPGSGHSRAPAATEVAA