Protein Info for PS417_09745 in Pseudomonas simiae WCS417

Annotation: peptide ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 316 transmembrane" amino acids 77 to 98 (22 residues), see Phobius details PF16220: DUF4880" amino acids 7 to 44 (38 residues), 47.9 bits, see alignment 9.6e-17 PF04773: FecR" amino acids 109 to 200 (92 residues), 85.2 bits, see alignment E=3.6e-28

Best Hits

KEGG orthology group: K07165, transmembrane sensor (inferred from 70% identity to pfo:Pfl01_3785)

Predicted SEED Role

"Antisigma transmembrane sensor FpvR" in subsystem Siderophore Pyoverdine

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UJ17 at UniProt or InterPro

Protein Sequence (316 amino acids)

>PS417_09745 peptide ABC transporter substrate-binding protein (Pseudomonas simiae WCS417)
MDNRARDEAAQWFVRLQDAELSIAERQRFDAWRNEHPDHQYEFDVLQGLWSATGLLPKAR
LQALCEAPVERPKRRAVLRYAVAAGVIAVALGLGLFSGLDHPKPYSAEFSTGVGEHRQVA
LPDGSVMDLNSRTVVAVQYEKGRRGVELKQGEAMFSVEHDTSRPFVVAAGAGQVTVTGTR
FDVRRDEGQTRVMVEAGTVKVQGDSPDNLVTLTAGLGTHVDNKGSVAAAYTVNTEELTAW
RTGKLVFNNALLGEVAREVSRYRERPLRVSTPAVGNLRLTSVFKANDTDALLKALPHILP
VALRTLPDGSQEIISR