Protein Info for GFF1907 in Variovorax sp. SCN45

Annotation: Transcriptional regulator, AraC family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 315 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF01965: DJ-1_PfpI" amino acids 3 to 168 (166 residues), 68.3 bits, see alignment E=1.1e-22 PF00165: HTH_AraC" amino acids 217 to 253 (37 residues), 36.3 bits, see alignment 7.2e-13 PF12833: HTH_18" amino acids 228 to 306 (79 residues), 72.3 bits, see alignment E=5e-24

Best Hits

KEGG orthology group: None (inferred from 82% identity to vpe:Varpa_4488)

Predicted SEED Role

"Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (315 amino acids)

>GFF1907 Transcriptional regulator, AraC family (Variovorax sp. SCN45)
MKRIGVLVFPGFQILDLAAIAAFELANMHLDQPVYCVEMLSETGGPVVSSSGVTVDSKRY
TAAKFDTLVMTGSLTITPTSEKLCQILRSGRRSARRVASICTGAFGLADAGLLDGRRVTT
HWAFAQELQRCHPLAKVQPDRIFINDDSLWTSAGMTAGIDLVLALVEEDLGVDMARLIAK
KLVVYHRRAGGQSQFSALLELEPKSDRIQLALAYARAHLREGLSVEELAEVAHLSPRQFS
RAFKAETGQSPAQAVESLRVEAARALIDEGRLALGVVAQEVGFGDPERMRRAFLRTLGQP
PQSVRRVARQQAMAA