Protein Info for GFF189 in Xanthobacter sp. DMC5

Annotation: Oligopeptide transport ATP-binding protein OppD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 329 PF00005: ABC_tran" amino acids 28 to 186 (159 residues), 103.5 bits, see alignment E=2.2e-33 TIGR01727: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain" amino acids 235 to 320 (86 residues), 68.7 bits, see alignment E=1.8e-23 PF08352: oligo_HPY" amino acids 237 to 301 (65 residues), 52.4 bits, see alignment E=8.3e-18

Best Hits

Swiss-Prot: 48% identical to Y3863_BRUME: Putative peptide import ATP-binding protein BMEII0863 (BMEII0863) from Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)

KEGG orthology group: K02031, peptide/nickel transport system ATP-binding protein (inferred from 91% identity to xau:Xaut_3377)

MetaCyc: 47% identical to murein tripeptide ABC transporter / oligopeptide ABC transporter ATP binding subunit OppD (Escherichia coli K-12 substr. MG1655)
3.6.3.23-RXN [EC: 7.4.2.6]; 7.4.2.6 [EC: 7.4.2.6]

Predicted SEED Role

"Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) (TC 3.A.1.5.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (329 amino acids)

>GFF189 Oligopeptide transport ATP-binding protein OppD (Xanthobacter sp. DMC5)
MAAVPTPLVDIRDLTIRFTGERTVHAVNGVSLSLGEGEVLGLLGESGSGKSVTMRALMRL
LPKRRSVISGSVHVAGQDVLAMDDATLSDFRGRTVSMIFQEPALALDPVYTIGRQISESV
MRHEGASQRDATARALEMLELVRIPSAKRRLDAYPHEMSGGMRQRAMIALALACRPKILL
ADEPTTALDATVQIQILLLLRELQREMGMSVIFVTHDIGVAIEICDKVAVMYAGQIVETG
TLGEIVRTPQHPYPRGLLASTVHGAARGARLETIPGTPPSLDKAPVACSFAPRCAFVQPR
CTVAPPPLVHLGPGRDVRCVLAETPVPVN