Protein Info for GFF1886 in Variovorax sp. SCN45

Annotation: Elongation factor G-like protein TM_1651

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 686 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details PF00009: GTP_EFTU" amino acids 15 to 265 (251 residues), 98.5 bits, see alignment E=1.1e-31 PF22042: EF-G_D2" amino acids 298 to 369 (72 residues), 48 bits, see alignment E=3.4e-16 PF14492: EFG_III" amino acids 392 to 464 (73 residues), 63.6 bits, see alignment E=4.3e-21 PF03764: EFG_IV" amino acids 467 to 585 (119 residues), 137.5 bits, see alignment E=5.9e-44 PF00679: EFG_C" amino acids 589 to 675 (87 residues), 85.1 bits, see alignment E=8.6e-28

Best Hits

KEGG orthology group: K02355, elongation factor G (inferred from 91% identity to vap:Vapar_5542)

Predicted SEED Role

"Translation elongation factor G-related protein" in subsystem Translation elongation factor G family

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (686 amino acids)

>GFF1886 Elongation factor G-like protein TM_1651 (Variovorax sp. SCN45)
MPSRSNGLAAEMEAVRTLALVGAAAAGKTSLAEALLFKAGAVKVCGSVERGSTVSDHDPL
ERRMQHSLNASVMHLTHAGTRIHLIDTPGGPDFLGQSLPTLEAVETVAVVINAAAGIEPM
AVRMMEYAASRHLARMIIVNKIDSQGVSLAGLLADIQITFGRECLPLNLPDGVGRQVVDC
FFNRFGQSDFGPVETAHRALVEQVVEVDAAFVDRYLEEGDVNPGELHAPLEQALREGHLI
PVCFVSSRSGAGVAELLDVIVKLLPDPTEANPPEFIVGEGAEAKPMQARPDPSLHVLAHV
FKVTIDPYVGKMGIFRVHQGTLSRDSQLYIGDGRKPFKVGHLFMLQGKDHVEVSHAVPGD
IVAVAKVDEIHFDAVLHDAAEDSHVHLAPLAFPVPVHGLAVEPKRHGDEQRAWEILGKLA
AEDPCLRIEHVMATNETVLYGLSELHLRIVLDRLREVYRFEVLTRPPRIAYRETVTAPAE
GHHRHKKQTGGAGQFGEVFLRIEPLARGGGFEFADEVRGGTIPGQFIPAVEKGVREVLVC
GAIAGYPVVDVRVVVYDGKHHSVDSKDIAFATAGRKAFMAAIREARPVVLEPIVQVEIVA
PEQSVGDVTSDLSTRRGLVTGTSAVGAGTVVVRGQVPMAELASYQSRLNAMTSGQGRYTM
ALSHYEAVPAATQQTLTGQYRVHEDD