Protein Info for GFF1863 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 transmembrane" amino acids 20 to 43 (24 residues), see Phobius details amino acids 55 to 74 (20 residues), see Phobius details amino acids 85 to 105 (21 residues), see Phobius details amino acids 114 to 135 (22 residues), see Phobius details amino acids 157 to 175 (19 residues), see Phobius details amino acids 181 to 201 (21 residues), see Phobius details amino acids 231 to 256 (26 residues), see Phobius details amino acids 262 to 285 (24 residues), see Phobius details amino acids 297 to 322 (26 residues), see Phobius details amino acids 330 to 353 (24 residues), see Phobius details amino acids 365 to 387 (23 residues), see Phobius details amino acids 397 to 415 (19 residues), see Phobius details PF07690: MFS_1" amino acids 29 to 384 (356 residues), 125.9 bits, see alignment E=8.8e-41

Best Hits

KEGG orthology group: None (inferred from 89% identity to vpe:Varpa_4493)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (437 amino acids)

>GFF1863 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MSPTTLSSPAFGPRHRWKVLAAGVAANAAFSVAFSGIPMTAVLMRTGYRLDNANLGLVLG
LMGLGIAVSELPWGLLTDRWGDRPVLLTGLGSTALALVAMALWAAPAAGHVPGLGWLGAG
LLLVGLLGGSVNGASGRAVMTWFDASERGLAMSIRQTAVPLGGGIGALVLPVVTLHFGFA
ALYGLLALLCALSAAMSWAWVHEPPIAPRGKAAAATEAAAPRSGPLRDARVWRIVAGIGI
LCAPQFAVLSFGTVFLHDFGHAGFAAITATMVFVQVGAMVMRVWSGRWTDRRRNRPAYLR
ACSGLSVLLFAGLALLVLLGGAHAADSSALRIALIVLLGASGVCVSAWHGVAYTELATLA
GAARAGTALGMANTSVFLVCFVTPFSIPHLMALQGWPLVWLAASACALVAMPLLVPRPVA
AAATDQNAAKTAFSRST