Protein Info for GFF1854 in Xanthobacter sp. DMC5

Annotation: Gamma-glutamylputrescine oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01266: DAO
  • amino acids 36 to 388 (353 residues), 185.7 bits, E=1.9e-58
• PF13450: NAD_binding_8
  • amino acids 39 to 68 (30 residues), 22.6 bits, see alignment (E = 1e-08)

Best Hits

KEGG orthology group: None (inferred from 68% identity to xau:Xaut_2412)

MetaCyc: 40% identical to pipecolate oxidase (Pseudomonas putida)
L-pipecolate oxidase. [EC: 1.5.3.7]

Predicted SEED Role

"L-pipecolate oxidase (1.5.3.7)" in subsystem Lysine degradation

MetaCyc Pathways

• L-lysine degradation II (L-pipecolate pathway) (2/9 steps found)
• L-lysine degradation V (2/9 steps found)
• superpathway of L-lysine degradation (13/43 steps found)

KEGG Metabolic Maps

• Lysine degradation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.5.3.7

Protein Sequence (434 amino acids)

>GFF1854 Gamma-glutamylputrescine oxidoreductase (Xanthobacter sp. DMC5)
MPPAPGTDPKSHGLWAMTAPPPPETAPLTGAARAADVAVVGAGYTGLAAALRLAEAGARV
TLLEAAGIGSGGAGRNVGLVNAGLWVMPDDIVATLGVERGEGLLSLLGGAPAEVFALVAR
HAIACEATPNGTLHCAVGRAGRAEIEARAAQWQARGAPVHLLDAEKARTMIGGGSYRGAL
LDDRAGTIQPLAYARGLARAAMGAGAVIHTASPVRAAEAGAGGWLLRTDGGTLAADWIIV
AGDAYSFGPWERLAREQVPLPYFNFATPPVPEALRQRILPGRPGIWDTQQVLTSLRYDAA
GRLVFGSIGALAGIEAGVHAAYARRALARLFPELPPAPFEAGWFGTIGMTDDALPRFRRL
ARNVVSISGYNGRGIGPGTVFGRLLADLVLGRVRPEEVPLPERDVTVPRWRAAKAAFYAA
GSAAAHLVGERRPA