Protein Info for GFF1834 in Sphingobium sp. HT1-2

Annotation: Integral membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 191 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 36 to 57 (22 residues), see Phobius details amino acids 74 to 95 (22 residues), see Phobius details amino acids 102 to 122 (21 residues), see Phobius details amino acids 150 to 180 (31 residues), see Phobius details PF06736: TMEM175" amino acids 5 to 89 (85 residues), 103.9 bits, see alignment E=2.5e-34

Best Hits

Swiss-Prot: 47% identical to TM175_CHRP1: Potassium channel HX13_20290 (HX13_20290) from Chryseobacterium sp. (strain P1-3)

KEGG orthology group: None (inferred from 80% identity to npp:PP1Y_Mpl9039)

Predicted SEED Role

"Integral membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (191 amino acids)

>GFF1834 Integral membrane protein (Sphingobium sp. HT1-2)
MNSKRLEAFTEGVIAIIITIMVLELKVPRGGSLADLAQCLPLLIAYLLSFVNVGLYWNNH
HHLFQLNPRIDGRVLWANLFLLFWLSLVPFVIRWLDESAWSTGATAAYGMVLGAAAIGYF
LTERAIIACNGAGSRLARALGMDWKGWGTLAIYGAAIPLSFVSRWLAVALYVLVVALWFV
PDRRFARVALP