Protein Info for GFF1829 in Sphingobium sp. HT1-2

Annotation: Exoenzymes regulatory protein AepA precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 642 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF22039: HUTI_composite_bact" amino acids 51 to 75 (25 residues), 30.4 bits, see alignment (E = 3.6e-11) PF07969: Amidohydro_3" amino acids 77 to 560 (484 residues), 440.9 bits, see alignment E=1.5e-135

Best Hits

KEGG orthology group: K07047, (no description) (inferred from 91% identity to npp:PP1Y_Mpl7385)

Predicted SEED Role

"Exoenzymes regulatory protein AepA precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (642 amino acids)

>GFF1829 Exoenzymes regulatory protein AepA precursor (Sphingobium sp. HT1-2)
VITRRDAMAGVAASALLSPFTAHAKDRPMTDTIIVNAKVTTLDRSNPVAEAVAIRDGKFL
AVGSEAEVRAAAPDATVIDAKGHRLIPGLIDSHMHIIRGGLNFNMELRWDGVPTLAEAMD
MLKAQVARTPAPQWVRVVGGFTEHQFAEKRLPTIAELNAVAPDTPVFILHLYDRALLNAA
ALRVVGYTKDTPNPPGGEIVRDAAGNPTGLLLAQPNATILYSTLAKGPKLPQDYQLNSTR
HFMRDVNALGVTGVIDAGGGFQNYPDDYEIIEKLHQDDQLTVRISYNLFTQKPKEELADF
SGWVKQVTPGQGDDSYRHNGAGEMLVYSAADFEDFRQPRPDMAPSMEGDLEPVIRLLAEH
KWPWRLHATYDETIGRALDVYEKVNRDIPLTGINWFFDHAETISDRNIDRIAALGGGIAV
QHRMAYQGEYFVERYGAKAAERTPPIARMIAAGIPVGAGTDATRVASYNPWVSLSWLVTG
RTVGGFALYRGDNRVSREKALAMWTHENTWFSNEIGKKGQIKAGQLADLALLSADYFAVP
EDQIVHIRSVLTLLGGKVVHGEGDYAPLAPDLPKPMPDWSPVATFGGYHKTREARAQLAS
ACGCHSACGVHGHDHAAALGADVPAADVQTFWGSLGCGCWAV