Protein Info for GFF1825 in Variovorax sp. SCN45

Annotation: Mg(2+) transport ATPase, P-type (EC 3.6.3.2)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 921 transmembrane" amino acids 103 to 121 (19 residues), see Phobius details amino acids 127 to 144 (18 residues), see Phobius details amino acids 310 to 331 (22 residues), see Phobius details amino acids 339 to 363 (25 residues), see Phobius details amino acids 728 to 755 (28 residues), see Phobius details amino acids 791 to 815 (25 residues), see Phobius details amino acids 826 to 844 (19 residues), see Phobius details amino acids 856 to 876 (21 residues), see Phobius details amino acids 888 to 907 (20 residues), see Phobius details TIGR01524: magnesium-translocating P-type ATPase" amino acids 53 to 921 (869 residues), 1340.8 bits, see alignment E=0 PF00690: Cation_ATPase_N" amino acids 59 to 119 (61 residues), 50.3 bits, see alignment 3.9e-17 PF00122: E1-E2_ATPase" amino acids 190 to 372 (183 residues), 135.8 bits, see alignment E=3.2e-43 TIGR01494: HAD ATPase, P-type, family IC" amino acids 289 to 430 (142 residues), 74.8 bits, see alignment E=4.9e-25 amino acids 634 to 751 (118 residues), 97.9 bits, see alignment E=4.8e-32 PF00702: Hydrolase" amino acids 388 to 676 (289 residues), 61.4 bits, see alignment E=4e-20 PF13246: Cation_ATPase" amino acids 436 to 502 (67 residues), 41 bits, see alignment 4.1e-14 PF00689: Cation_ATPase_C" amino acids 745 to 911 (167 residues), 71.2 bits, see alignment E=2.4e-23

Best Hits

KEGG orthology group: K01531, Mg2+-importing ATPase [EC: 3.6.3.2] (inferred from 65% identity to axy:AXYL_01000)

Predicted SEED Role

"Mg(2+) transport ATPase, P-type (EC 3.6.3.2)" (EC 3.6.3.2)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.2

Use Curated BLAST to search for 3.6.3.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (921 amino acids)

>GFF1825 Mg(2+) transport ATPase, P-type (EC 3.6.3.2) (Variovorax sp. SCN45)
MKNVLKSFFESFLRSRHMLHHFERWQTLLGSKPAASGSVSMPADIAKALDAASRTDAGEM
LVKLHSSPRGLSEGHAQVLHKRLGSNEVRHEKPLPWWQHLWQCYRNPFNLLLTVLALISY
VTDDMKAALVIGSMVVLSTVLRFLQESRSNKAAERLKAMVSNTSTVLRPAPGQKAGSAGD
EGFDATHAGTVRVEVPMRDLVPGDVIALSAGDMVPADCRLLTAKDLFISQSALTGEAMPV
EKFVVDRGDHGAGVLERENLLFMGTNVISGTATALIVHTGDRTFFGALAQRVTATDRGTS
AFQAGINRVSWVLIRFMLVMAPLVLVINGVAKGDWWEAALFALSIAVGLTPEMLPMIVTA
TLAKGAVVMSRQKVIVKRLEAIHNFGAMDVLCTDKTGTLTQDRIVLERHTNAWGEASEHV
LQLAYLNSFHQTGLKNLLDKAVLSHAEMQLETRLQTSYRKIDEVPFDFSRRRMSVVVANG
GSEHLLICKGALEEILSVCTSVERGAEVLALDDEVLARIHRVASQLNAQGLRVVAVASRA
LKLEAQKPAYGVADESGLTLLGYVAFLDPPKESTAPALRALAEHGVGVKVLTGDNELVTR
KVCGDVGIEAGRMVLGHEIEDMSEADLRVLVERHQVFAKLTPAHKERIVQALHANGHVVG
FMGDGINDAPALRAADIGISVDGAVDVAKESADIILLEKSLMVLEQGVIEGRRTFANMLK
YIKITASSNFGNVFSVLVASAFLPFLPMLPLHLLVQNLLYDVSQIAIPFDNVDDEFLKNP
QRWNPADLGRFMVFFGPLSSVFDILTFTVLWFVFAANSVDHQTLFQSGWFVEGLLSQTLI
VHLIRTRKIPFLQSRASWPMLAMGAAIAAVGIWLPMGPLSHYFKLQALPLAYVPWLVAML
VGYAVLTQTVKGWYGRRYGWQ