Protein Info for GFF1819 in Xanthobacter sp. DMC5

Annotation: Putative membrane-bound redox modulator Alx

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 330 transmembrane" amino acids 17 to 38 (22 residues), see Phobius details amino acids 50 to 70 (21 residues), see Phobius details amino acids 89 to 107 (19 residues), see Phobius details amino acids 115 to 137 (23 residues), see Phobius details amino acids 143 to 161 (19 residues), see Phobius details amino acids 205 to 227 (23 residues), see Phobius details amino acids 242 to 262 (21 residues), see Phobius details amino acids 274 to 293 (20 residues), see Phobius details amino acids 299 to 318 (20 residues), see Phobius details TIGR03718: integral membrane protein, TerC family" amino acids 16 to 320 (305 residues), 388.7 bits, see alignment E=1.1e-120 PF03741: TerC" amino acids 81 to 290 (210 residues), 170.6 bits, see alignment E=1.4e-54

Best Hits

Swiss-Prot: 45% identical to Y082_RICBR: Uncharacterized membrane protein RBE_0082 (RBE_0082) from Rickettsia bellii (strain RML369-C)

KEGG orthology group: K05794, tellurite resistance protein TerC (inferred from 83% identity to azc:AZC_3016)

Predicted SEED Role

"Integral membrane protein TerC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (330 amino acids)

>GFF1819 Putative membrane-bound redox modulator Alx (Xanthobacter sp. DMC5)
MDQLIALLFLDVAGEPLWLWLGFLAIVFALLAFDLGVLHRDSREIGIAESLRLSVFYIAV
AAVFGGWIWASMGPQAGMQYFTGYAIEKALSIDNVFVISLIFSYFAIPRAYQYRALVWGI
IAVLVLRGLMIGVGAALVQSYDWVLLLFGAFLVVTGIKMLFASEGETDISQNAALRFLTK
RMRVTQELHGERFFVRQPHPVTGKAVLWATPLFFALVVINIADFVFAVDSVPAIFAITTD
TYIVFTANIMAILGLRALYFALAAMVHRFSHLKYALAGVLVFIGGKIFWSHFFGKVDPAI
SLGVTVAMIAAGILFSLWRTGGGTDVKHAA