Protein Info for GFF1811 in Xanthobacter sp. DMC5

Annotation: Putative cation/proton antiporter YbaL

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 616 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 33 to 51 (19 residues), see Phobius details amino acids 57 to 77 (21 residues), see Phobius details amino acids 87 to 108 (22 residues), see Phobius details amino acids 114 to 136 (23 residues), see Phobius details amino acids 149 to 174 (26 residues), see Phobius details amino acids 194 to 215 (22 residues), see Phobius details amino acids 235 to 269 (35 residues), see Phobius details amino acids 286 to 307 (22 residues), see Phobius details amino acids 314 to 336 (23 residues), see Phobius details amino acids 343 to 365 (23 residues), see Phobius details amino acids 377 to 396 (20 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 16 to 390 (375 residues), 179.3 bits, see alignment E=1.1e-56 PF02254: TrkA_N" amino acids 436 to 549 (114 residues), 81.1 bits, see alignment E=7.9e-27

Best Hits

KEGG orthology group: K03455, monovalent cation:H+ antiporter-2, CPA2 family (inferred from 61% identity to rle:RL0682)

Predicted SEED Role

"TrkA-N:Sodium/hydrogen exchanger" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (616 amino acids)

>GFF1811 Putative cation/proton antiporter YbaL (Xanthobacter sp. DMC5)
LPHDTPLIATLVGAFVLAFVLGAVAQRLKLSPLVGYLLAGVLVGPFTPGFVADEHLALEL
AEIGVILLMFGVGLHFSLSDLLSVKAIAIPGAIVQIGVATAMGIGLTWAMGWSLGAGIVF
GIALSVASTVVLLRALQERRMVESEQGRIAVGWLIVEDLAMVLALVLLPALSGALGGRTV
TTGTIDWLGLGGDVWTTLAVTLVKVAGFVVLMLVVGRRVIPWIMHWVAHIGSRELFRLAV
LAIALGVAFGSAKLFGVSFALGAFFAGMVLSESPLSHRAAEETLPLRDAFAVLFFVSVGM
LVDPSIVLKSPIPLLVTVLIVLFGKSIAAFLIVRAFGYGNSTAFTISASLAQIGEFSFIL
VALGVDLQLLPAEGRDLILAAAIISILANPFFFLVLDRYRARQAPLRPEKTPAAAPAPAP
KPVPALPETALTNHTVLVGYGRVGRLVADGLKAAGTPFLVIEDQGDRLEELKRMGLEAVN
ANAASAPAITAANVAGARRIILAIPDGFEASNVLKKARQLNPGIEIVARAHSDAEVEHLR
QSGANFIIMGEREVARGMLAHVLETSQNDIAAAAAAEQAVEGGNRADPSVPFPSGPSVEA
APGLAEPAAAAQKETL