Protein Info for GFF1806 in Xanthobacter sp. DMC5

Annotation: 33 kDa chaperonin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 PF01430: HSP33" amino acids 20 to 325 (306 residues), 251.3 bits, see alignment E=6.3e-79

Best Hits

KEGG orthology group: K04083, molecular chaperone Hsp33 (inferred from 84% identity to xau:Xaut_1220)

Predicted SEED Role

"Chaperone protein Hsp33"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (335 amino acids)

>GFF1806 33 kDa chaperonin (Xanthobacter sp. DMC5)
MKGERTRTATRAASEATQDDIVTAFQVDALDIRGRTVRLGPTLDALLAHHAYPPAVKRVV
GEAVTLAVLLGSSLKFEGRFILQTQTDGPVDMVVADFVSPDKIRAYARYDADALAEAERR
NETSPAALLGRGHLAMTIDQGISTNRYQGVVALDGSGLEAAAHEYFHQSEQIPTRVRLAV
GEEMKPGGAESSWRAGGLLAQFLPQDASRARMADLSPGDAPEGVEEHKVDEDDAWVEARS
LVGTLEDVELIDRDLSSERLLYRLFHERGVRVFDPLPIAARCSCSREKVSGVLASFGPEE
RREMIQDDGKVTVTCEFCGRTYKFTAEEVLGQADG