Protein Info for GFF1798 in Xanthobacter sp. DMC5

Annotation: putative GTP-binding protein EngB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 218 TIGR03598: ribosome biogenesis GTP-binding protein YsxC" amino acids 26 to 210 (185 residues), 208.2 bits, see alignment E=4.3e-66 PF01926: MMR_HSR1" amino acids 44 to 162 (119 residues), 70.9 bits, see alignment E=1.9e-23

Best Hits

Swiss-Prot: 63% identical to ENGB_OLICO: Probable GTP-binding protein EngB (engB) from Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / KCTC 32145 / OM5)

KEGG orthology group: K03978, GTP-binding protein (inferred from 88% identity to xau:Xaut_0361)

Predicted SEED Role

"GTP-binding protein EngB" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (218 amino acids)

>GFF1798 putative GTP-binding protein EngB (Xanthobacter sp. DMC5)
MTETPSPADADPYLEPGRLLFAGDWQFVSAAPTVEVLPPMQGMEIALAGRSNVGKSSLVN
ALTGRKALARTSVTPGRTQELIFFRVGPELCLVDMPGYGFAKAPKEKVDAWTRTIKDYLR
GRVNLARVFVLIDSRHGIKPVDEEILDLLDKAAVSYAIILTKVDQVKPSALPSVIAGVED
KIRRRPAAYPKIFPTSSNTGQGFPELRAAVAQLLAEQG