Protein Info for GFF1797 in Xanthobacter sp. DMC5

Annotation: Biosynthetic peptidoglycan transglycosylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 741 transmembrane" amino acids 85 to 110 (26 residues), see Phobius details PF00912: Transgly" amino acids 147 to 311 (165 residues), 219.1 bits, see alignment E=3.1e-69 TIGR02074: penicillin-binding protein, 1A family" amino acids 149 to 668 (520 residues), 608.6 bits, see alignment E=5.9e-187 PF00905: Transpeptidase" amino acids 399 to 642 (244 residues), 120.6 bits, see alignment E=8.1e-39

Best Hits

KEGG orthology group: None (inferred from 82% identity to xau:Xaut_0362)

Predicted SEED Role

"Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)" in subsystem Peptidoglycan Biosynthesis or Type IV pilus (EC 2.4.1.129, EC 3.4.-.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129, 3.4.-.-

Use Curated BLAST to search for 2.4.1.129 or 3.4.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (741 amino acids)

>GFF1797 Biosynthetic peptidoglycan transglycosylase (Xanthobacter sp. DMC5)
MTAQGRGDGMRREPLMERPESLFDIRLDPRDRSAAPPPEPPRPARKPAARPKAKAEPDMR
PDPAPRRGRSEPPPRRPRRGGGGRLVFRLVKWGFILGMWALLALAGVIAYEASKLPPMQT
LMIPKRPPTVTVQGADGKTIATRGDMGGVAVPIGELPPYLPKAFVAIEDQRFYSHFGLDP
EGLARALVTNLTSRRLRQGGSTLTQQLAKNLFLTQERTASRKMQELVLALWLEHKFSKDQ
LLDLYLNRVYFGAGAYGVEAAAQRYFGKSARQVTLAEAAMLAGLVNSPSRLAPTRNLKGA
QTRANLVLAAMRDQKMISADMASTAQARPAQLARSGMPDSSGYVADWVMDQLDSVLGDGE
LPGDVTVRTTIDPALQKAGEAALEDTLAKSGTKYGVGQGAIVVLDPDGGVKALIGGRSYA
DSQYNRAVTARRQPGSAFKPFIYLTAVEHGLNPESVREDAPIQLKGWRPENSTRDYRGPV
TLTTALALSLNTVSVRLVLEFGPKAVVQTAHRMGISSNLDPNPSIALGTSEVSVLELAGA
YTPFANGGLGVMPHVIDSVIGPDGKPLYERNVTGMGRVVASEYVAMMNHMMTQTLATGTA
RRADLPGWEAAGKTGTSQDYRDAWFVGYTAKYVTAVWLGNDDSSPTKKASGANLPVEIWS
RVMKAAHQGVPVAELPGGLRSYGFGGNGYGQPGATYLPPADMPDDRPSAVVGQMPAPPPQ
QEPPMTLDRWFAETFLGQGRR