Protein Info for GFF177 in Sphingobium sp. HT1-2

Annotation: LPS-assembly protein LptD @ Organic solvent tolerance protein precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 754 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF03968: LptD_N" amino acids 64 to 109 (46 residues), 23.7 bits, see alignment 4.7e-09 PF04453: LptD" amino acids 314 to 681 (368 residues), 226.3 bits, see alignment E=8.4e-71

Best Hits

KEGG orthology group: K04744, LPS-assembly protein (inferred from 77% identity to sch:Sphch_1582)

Predicted SEED Role

"Outer membrane protein Imp, required for envelope biogenesis / Organic solvent tolerance protein precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (754 amino acids)

>GFF177 LPS-assembly protein LptD @ Organic solvent tolerance protein precursor (Sphingobium sp. HT1-2)
LQISVFPLSFKQALLAGAASSCLLAAPLAHAQQAPEPKLNEPQTPISAPDAPVPDNDQEI
GFAADTLEYDTNSQVVTATGNVQLLRDGNRLRADKIVWDRNTGKVEAQGAVSVIDPDGNV
AYGDRFDVTDTLKDGAVDNILLVLQKGGRMAATKGERVNGVYTLHHAAYTGCPVEGSDGC
PKEPTWQINAVKVVYDPTKQRVSYTRANVELFGLPLIPVPGLSHPVGDDGGSGLLVPNIR
YDRVNGFEVAVPYYLKLAPNRDLTVTPHVYSDSLPMIEGNFRHLYDRGAYQITGYATYGS
RSSGITPTDSQKDIRGAIDASGGMQLSPEWSVNGSIRVATDRTFLRRYDISRDDRLRSTL
GVQRIGENSYFSLAGWAVQTLRVDDPQGQMPIALPVMDYRLRMKDPLLGGQIQFQANTLA
ITRTEGQDTQRAFAAFEWNLRKLTGLGQEVNFTTYLRGDVYHSSDNLLTDTISYAGDPGW
KARGIAAAAVDMRWPFMGEAFGGVQRIAPRVQIVASPHLANLSVPNEDARSVDLEDSNLF
ALNRFAGYDRFEDSSRITYGLEYNLALPDFTLDANVGQSYRLDNRASILPDGTGLSDRMS
DIVGRWTIRYKDFVSFTQRFRVDKDNLAVRRNEVDATVGSKKTYAQISYLRLNRNANITL
EDLQDREELRLGGRIQFARFWSVFGSTVIDLTGAQEDPGTTADGYEPVRQRLGVAYEDDC
LTLGFTWRRDYQTNGDARAGNSFQLRLAFRNIGI