Protein Info for GFF1766 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 406 PF02353: CMAS" amino acids 113 to 385 (273 residues), 335.4 bits, see alignment E=1.2e-103 PF08123: DOT1" amino acids 151 to 216 (66 residues), 28.4 bits, see alignment E=5.1e-10 PF13489: Methyltransf_23" amino acids 163 to 291 (129 residues), 58.5 bits, see alignment E=3.2e-19 PF01135: PCMT" amino acids 165 to 244 (80 residues), 22.8 bits, see alignment E=3.3e-08 PF05175: MTS" amino acids 166 to 244 (79 residues), 23.8 bits, see alignment E=1.4e-08 PF13847: Methyltransf_31" amino acids 173 to 273 (101 residues), 36.5 bits, see alignment E=1.8e-12 PF08241: Methyltransf_11" amino acids 178 to 274 (97 residues), 55 bits, see alignment E=5e-18 PF08242: Methyltransf_12" amino acids 178 to 273 (96 residues), 48.2 bits, see alignment E=7e-16 PF13649: Methyltransf_25" amino acids 178 to 272 (95 residues), 64.2 bits, see alignment E=6.6e-21

Best Hits

KEGG orthology group: K00574, cyclopropane-fatty-acyl-phospholipid synthase [EC: 2.1.1.79] (inferred from 65% identity to bvi:Bcep1808_2663)

Predicted SEED Role

"Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)" (EC 2.1.1.79)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.79

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (406 amino acids)

>GFF1766 Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MGSIVERALLPWAQRVKTRVNLPVRLSWGERGSSSLSLGEFEAPQVEIRVRDASALPLLI
DPGLDTLGQAYVEGLIDVDGSMADILAVAHRLAETAEPDGGLLGRLRRRFAHTRESDSEA
IQYHYDVSNAFYAQWLDERMVYSCGYFENGDETLDEAQVKKIDHILTKIQLQPGQRLLDI
GCGWGALVLRAAQKFGAHCVGVTLSKNQHELARERVKAAGLEDRIDIRLQDYRDVKDGPF
DRITSVGMFEHVGLNHLAAYFGHIRSLLKPDGWAMNHGITSTDPHDGETRHGGGTFIDRY
VFPQGELPHIGTVLRTMQEGGLEAFDIESLRRHYMRTTQLWSEAFEARTAQIKPLVDERK
WRIWRVYLAGCAWAFEHDEVSIYQVICRAAGQPAQGLPWSRRFMYR