Protein Info for GFF1763 in Variovorax sp. SCN45

Annotation: HemK family modification methylase PA2179

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 317 PF13847: Methyltransf_31" amino acids 132 to 209 (78 residues), 29.4 bits, see alignment E=1.2e-10 PF05175: MTS" amino acids 133 to 249 (117 residues), 49.8 bits, see alignment E=6.6e-17 PF06325: PrmA" amino acids 133 to 206 (74 residues), 24.1 bits, see alignment E=5e-09 PF13649: Methyltransf_25" amino acids 134 to 214 (81 residues), 33 bits, see alignment E=1.6e-11

Best Hits

KEGG orthology group: None (inferred from 51% identity to mpo:Mpop_2378)

Predicted SEED Role

"HemK family modification methylase PA2179"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (317 amino acids)

>GFF1763 HemK family modification methylase PA2179 (Variovorax sp. SCN45)
MLNAAGVLRQVAATGYRFTTVTPLTHQRVLARRGREPGTTLRDVFGWNLPFEAGALPPGL
LAEMEQAGIVRRNGSLLRSTVRIASLGDDLFFHSAYPTVEENAVFFGPDTSRFARFVGHA
LQERKPRGPGPLRVLDIGCGSGAGGIVAARSLADAGVASTVVMNDINPLALRYTSVNAEV
AGVPVTLAQGDALSAVQGAFDLIISNPPYLDDAAQRAYRHGGARLGRALGARIAAESLKR
LAPGGQLLLYTGVAMVDGEDPFIAELQPLLQASGCEWSYTEIDPDVFGEELERPVYAHID
RIAAVGLVASRAAEAAP