Protein Info for GFF1758 in Sphingobium sp. HT1-2

Annotation: Peptidase M28

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 555 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF04389: Peptidase_M28" amino acids 301 to 512 (212 residues), 151.4 bits, see alignment E=2.6e-48

Best Hits

KEGG orthology group: None (inferred from 72% identity to swi:Swit_2578)

Predicted SEED Role

"Aminopeptidase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (555 amino acids)

>GFF1758 Peptidase M28 (Sphingobium sp. HT1-2)
MKHALPLLALGLATLSFPANAQTDPAKTDPAKLEQSVRTMASDLFEGRAPGTVGEERTIG
YLVARFEQLGLEPGGPDGQWVQTVPLLHTRLGQSESLSVAQNGAATPWTFGKQVYLSTLQ
PKDKVAVANAPMVFVGYGVSAPERGWDDFKGVDLKGKIAVFLINDPDFEASKGEDPFGKF
GGKTMTYYGRWTYKFEEAARHGAIGALIVHDTPGAGYGWNVVVSPGGENYDLVRPADKLT
SLQVQGWVEGEAAKALFAGAGQDLAALRKQARSAKFKPVELKGASFSAAFPVTQEVVKSA
NVIARIPGAKRPDETVMYGAHWDAYGKGAPDAQGRIYRAGANDDALGMAGLFEIARIFKA
GPAPDRSIVFAAWTAEERGLLGSEFYAQNPVYPLDKTVANLTIDVLQTAGKAKDVILIGK
GQNVLEDDLAKFAAKQGRVITQESLPERGLFYRADHFSMAKRGVPVLLMMGLAGASDMID
GGRAAGQAWIDAYTGKCYHQACDAVDDTWKLDGAAQDVDLMYDIGRDLAFSARWPEWKTG
SEFKAIRDKSAAVRK